Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 6/20 | 0.50 |
| ▸ | LAP3 | P28838 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ANPEP | P15144 | 4/20 | 0.37 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | METAP1 | P53582 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5496511 | 1.00 | FDPS (0.50) | FDPSLAP3LMNAANPEPERAP1 | |
| SCHEMBL5572484 | 0.97 | FDPS (0.48) | FDPSLAP3LMNAANPEPERAP1 | |
| SCHEMBL4436425 | 0.84 | FDPS (0.42) | FDPSLAP3LMNAANPEPERAP1 | |
| SCHEMBL5059565 | 0.79 | FDPS (0.46) | FDPSLAP3LMNAANPEPERAP1 | |
| SCHEMBL6663397 | 0.79 | FDPS (0.38) | FDPSLAP3LMNA | |
| SCHEMBL7511455 | 0.77 | LMNA (0.45) | FDPSLAP3LMNAALDH1A1 | |
| SCHEMBL16091906 | 0.74 | FDPS (0.52) | FDPSLAP3LMNAANPEPERAP1 | |
| SCHEMBL5318557 | 0.72 | FDPS (0.46) | FDPSLAP3LMNAANPEPERAP1 | |
| SCHEMBL6132043 | 0.72 | LAP3 (0.46) | FDPSLAP3LMNAMETAP1ADRB3 | |
| SCHEMBL5489929 | 0.72 | LAP3 (0.46) | FDPSLAP3LMNAMETAP1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0177443-B1 | CRYSTAL MODIFICATION OF DISODIUM-3-AMINO-1-HYDROXY-PROPANE-1,1-DIPHOSPHONATE | CIBA-GEIGY AG (CH) | 1989-10-18 | — | — | EP | claimed |
| CN-116253759-A | Method for preparing pamidronate disodium by one-pot method | 仁合益康集团有限公司 | 2023-06-13 | — | — | CN | disclosed |
| CN-103030661-A | Method for preparing sodium ibandronate | FANGSHENG PHARMACEUTICAL CO LTD | 2013-04-10 | — | — | CN | disclosed |
| EP-2046342-A2 | CRYSTALLINE FORM A OF IBANDRONIC ACID AND PROCESS FOR THE PREPARATION | Dr. Reddy's Laboratories Ltd. (IN) | 2009-04-15 | — | — | EP | disclosed |
| US-7411087-B2 | Process for preparation of bisphosphonic acid compounds | SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) | 2008-08-12 | — | — | US | disclosed |
| WO-2008014510-A2 | CRYSTALLINE FORM A OF IBANDRONIC ACID AND PROCESS FOR THE PREPARATION | DR. REDDY'S LABORATORIES LIMITED (IN) | 2008-01-31 | — | — | WO | disclosed |
| EP-0593437-A1 | GEM-DIPHOSPHONIC ACIDS, A PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. | BOEHRINGER MANNHEIM ITALIA (IT) | 1994-04-27 | — | — | EP | disclosed |
| US-4104366-A | Compositions for preparation of aqueous solutions of low valence 99 technitium salts | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1978-08-01 | — | — | US | disclosed |