Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | ELANE | P08246 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.50 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1820544 | 0.91 | LMNA (0.58) | ALDH1A1RAB9ASMN1; SMN2HTTNPSR1 | |
| SCHEMBL27003 | 0.91 | LMNA (0.58) | ALDH1A1RAB9ASMN1; SMN2HTTNPSR1 | |
| SCHEMBL1093883 | 0.91 | LMNA (0.58) | ALDH1A1RAB9ASMN1; SMN2HTTNPSR1 | |
| Methane SCHEMBL9356267 | 0.89 | LMNA (0.56) | ALDH1A1RAB9ASMN1; SMN2HTTNPSR1 | |
| SCHEMBL27719890 | 0.89 | LMNA (0.56) | ALDH1A1RAB9ASMN1; SMN2HTTNPSR1 | |
| SCHEMBL16222220 | 0.85 | ALDH1A1 (0.61) | ALDH1A1SRD5A2RAB9AHPGDELANE | |
| Benzophenone SCHEMBL29127482 | 0.84 | ALDH1A1 (0.74) | ALDH1A1SRD5A2RAB9AHPGDELANE | |
| SCHEMBL21456599 | 0.84 | KDM4E (0.43) | ALDH1A1RAB9AHPGDSMN1; SMN2HTT | |
| Benzophenone SCHEMBL1889872 | 0.83 | ALDH1A1 (0.64) | ALDH1A1SRD5A2RAB9AHPGDELANE | |
| Benzophenone SCHEMBL28744509 | 0.82 | ALDH1A1 (0.70) | ALDH1A1SRD5A2RAB9AHPGDELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4496447-A | PHOTOPOLYMERIZATION OF UNSATURATED COMPOUNDS AND FOR CURING PRINTING INKS | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1985-01-29 | — | — | US | disclosed |
| US-4374984-A | Aromatic-aliphatic ketones useful as photoinitiators | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1983-02-22 | — | — | US | disclosed |