Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | CES2 | O00748 | 4/20 | 0.58 |
| ▸ | CES1 | P23141 | 4/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | PGR | P06401 | 1/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.53 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | HRH1 | P35367 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 2/20 | 0.48 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.48 |
| ▸ | XBP1 | P17861 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1093883 | 1.00 | LMNA (0.58) | LMNACES2CES1TDP1L3MBTL1 | |
| SCHEMBL27003 | 1.00 | LMNA (0.58) | LMNACES2CES1TDP1L3MBTL1 | |
| Methane SCHEMBL9356267 | 0.98 | LMNA (0.56) | LMNACES2CES1TDP1L3MBTL1 | |
| SCHEMBL27719890 | 0.98 | LMNA (0.56) | LMNACES2CES1TDP1L3MBTL1 | |
| SCHEMBL10944827 | 0.91 | ALDH1A1 (0.58) | LMNACES2CES1TDP1L3MBTL1 | |
| Acrylic Acid SCHEMBL28676895 | 0.88 | AKT1 (0.50) | LMNACES2CES1TDP1L3MBTL1 | |
| SCHEMBL21456599 | 0.87 | KDM4E (0.43) | LMNACES2CES1PGRADRA2A | |
| SCHEMBL29234971 | 0.84 | LMNA (0.44) | LMNACES2CES1TDP1L3MBTL1 | |
| Phenylglycine SCHEMBL28088318 | 0.83 | LMNA (0.52) | LMNACES2CES1TDP1L3MBTL1 | |
| Piperidine SCHEMBL6693285 | 0.83 | LMNA (0.43) | LMNACES2CES1TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2316926-B1 | Enantioselective production of alpha-hydroxy carbonyl compounds | UNIV BONN (DE) | 2016-04-13 | — | — | EP | claimed |
| EP-2316926-A1 | Enantioselective production of alpha-hydroxy carbonyl compounds | Rheinische Friedrich-Wilhelms-Universität Bonn (DE) | 2011-05-04 | — | — | EP | claimed |
| EP-0643781-B1 | ELECTROCATALYTIC ASYMMETRIC DIHYDROXYLATION OF OLEFINIC COMPOUNDS | SEPRACOR INC (US) | 1998-06-24 | — | — | EP | claimed |
| EP-0643781-A1 | ELECTROCATALYTIC ASYMMETRIC DIHYDROXYLATION OF OLEFINIC COMPOUNDS | SEPRACOR, INC. (US) | 1995-03-22 | — | — | EP | claimed |
| WO-1993017150-A1 | ELECTROCATALYTIC ASYMMETRIC DIHYDROXYLATION OF OLEFINIC COMPOUNDS | SEPRACOR, INC. (US) | 1993-09-02 | — | — | WO | claimed |
| CN-116731985-A | Cytochrome P450 monooxygenase P450PL2 mutant and application thereof | 中国科学院新疆理化技术研究所 | 2023-09-12 | — | — | CN | disclosed |
| EP-2316926-B1 | Enantioselective production of alpha-hydroxy carbonyl compounds | UNIV BONN (DE) | 2016-04-13 | — | — | EP | disclosed |
| EP-2316926-A1 | Enantioselective production of alpha-hydroxy carbonyl compounds | Rheinische Friedrich-Wilhelms-Universität Bonn (DE) | 2011-05-04 | — | — | EP | disclosed |
| EP-1048737-B1 | Stereoselective synthesis of 2-hydroxycétones | FORSCHUNGSZENTRUM JUELICH GMBH (DE) | 2007-06-06 | — | — | EP | disclosed |
| US-7166749-B2 | Process for preparing chiral aromatic α-hydroxy ketones using 2-hydroxy-3-oxoacid synthase | BEN-GURION UNIVERSITY OF THE NEGEV (IL) | 2007-01-23 | — | — | US | disclosed |
| US-7166749-B2 | Process for preparing chiral aromatic α-hydroxy ketones using 2-hydroxy-3-oxoacid synthase | BEN-GURION UNIVERSITY OF THE NEGEV (IL) | 2007-01-23 | — | — | US | disclosed |
| US-7045334-B2 | Nucleotide sequence encoding a benzaldehyde lyase, and process for stereoselectively synthesizing 2-hydroxyketones | Forschungszentrum Jülich GmbH (DE) | 2006-05-16 | — | — | US | disclosed |
| EP-0643781-A4 | ELECTROCATALYTIC ASYMMETRIC DIHYDROXYLATION OF OLEFINIC COMPOUNDS. | — | 1995-04-26 | — | — | EP | disclosed |
| EP-0643781-A1 | ELECTROCATALYTIC ASYMMETRIC DIHYDROXYLATION OF OLEFINIC COMPOUNDS | SEPRACOR, INC. (US) | 1995-03-22 | — | — | EP | disclosed |
| US-5302257-A | Preparing optically active glycols using catalyst complex of osmium tetroxide and chiral oxidation resistant tertiary amine, employing secondary oxidant to generate osmium tetroxide, electrolytically regenerating secondary oxidant | SEPRACOR, INC. (US) | 1994-04-12 | — | — | US | disclosed |
| WO-1993017150-A1 | ELECTROCATALYTIC ASYMMETRIC DIHYDROXYLATION OF OLEFINIC COMPOUNDS | SEPRACOR, INC. (US) | 1993-09-02 | — | — | WO | disclosed |
| WO-1992017433-A1 | PREPARATION OF CHIRAL HYDROXYKETONES | SCHERING CORPORATION (US) | 1992-10-15 | — | — | WO | disclosed |
| EP-0506341-A1 | Preparation of chiral hydroxyketones | SCHERING CORPORATION (US) | 1992-09-30 | — | — | EP | disclosed |
| EP-0400239-A1 | Process for asymmetric reduction of ketones with baker's yeast | Daito Corporation (JP) | 1990-12-05 | — | — | EP | disclosed |
| EP-0051061-A2 | Novel intermediates and process for their preparation | THE WELLCOME FOUNDATION LIMITED (GB) | 1982-05-05 | — | — | EP | disclosed |