Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | CES2 | O00748 | 4/20 | 0.56 |
| ▸ | CES1 | P23141 | 4/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | PGR | P06401 | 1/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.52 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | HRH1 | P35367 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27003 | 0.98 | LMNA (0.58) | LMNACES2CES1TDP1L3MBTL1 | |
| SCHEMBL1093883 | 0.98 | LMNA (0.58) | LMNACES2CES1TDP1L3MBTL1 | |
| SCHEMBL1820544 | 0.98 | LMNA (0.58) | LMNACES2CES1TDP1L3MBTL1 | |
| SCHEMBL27719890 | 0.95 | LMNA (0.56) | LMNACES2CES1TDP1L3MBTL1 | |
| SCHEMBL10944827 | 0.89 | ALDH1A1 (0.58) | LMNACES2CES1TDP1L3MBTL1 | |
| Acrylic Acid SCHEMBL28676895 | 0.86 | AKT1 (0.50) | LMNACES2CES1TDP1L3MBTL1 | |
| SCHEMBL21456599 | 0.85 | KDM4E (0.43) | LMNACES2CES1PGRADRA2A | |
| SCHEMBL29234971 | 0.82 | LMNA (0.44) | LMNACES2CES1TDP1L3MBTL1 | |
| Phenylglycine SCHEMBL28088318 | 0.81 | LMNA (0.52) | LMNACES2CES1TDP1L3MBTL1 | |
| Piperidine SCHEMBL6693285 | 0.81 | LMNA (0.43) | LMNACES2CES1TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0332400-B1 | Photocurable organopolysiloxane composition | SHINETSU CHEMICAL CO (JP) | 1994-11-30 | — | — | EP | disclosed |
| US-4943613-A | Photocurable organopolysiloxane composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1990-07-24 | — | — | US | disclosed |
| EP-0332400-A2 | Photocurable organopolysiloxane composition | Shin-Etsu Chemical Co., Ltd. (JP) | 1989-09-13 | — | — | EP | disclosed |