SCHEMBL10947342

SCHEMBL10947342

CN(C(O)=S)c1cccc(Br)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 1/20 0.41
PHGDH O43175 1/20 0.41
MGLL Q99685 1/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA9 Q16790 1/20 0.41
MTNR1A P48039 1/20 0.41
MTNR1B P49286 1/20 0.41
ALDH1A1 P00352 3/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
KDM4E B2RXH2 2/20 0.41
SIGMAR1 Q99720 3/20 0.40
LMNA P02545 3/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
HTR3E A5X5Y0 1/20 0.40
HTR3B O95264 1/20 0.40
HTR3A P46098 1/20 0.40
HTR3D Q70Z44 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1400933 0.81 MTNR1A (0.48) MTNR1AMTNR1BALDH1A1MEN1KMT2A
SCHEMBL10939448 0.80 ALDH1A1 (0.52) FAAHPHGDHMGLLCA12CA1
SCHEMBL10942171 0.78 HTR3E (0.62) FAAHPHGDHMGLLCA12CA1
SCHEMBL10476834 0.78 LMNA (0.53) FAAHPHGDHMGLLCA12CA1
SCHEMBL10940414 0.77 FAAH (0.41) FAAHPHGDHMGLLCA12CA1
SCHEMBL2378380 0.77 MTNR1A (0.48) MTNR1AMTNR1BALDH1A1MEN1KMT2A
SCHEMBL8848450 0.77 FAAH (0.64) FAAHPHGDHMGLLCA12CA1
SCHEMBL10947337 0.76 MTNR1A (0.43) MTNR1AMTNR1BALDH1A1MEN1KMT2A
SCHEMBL11541741 0.76 MTNR1A (0.43) MTNR1AMTNR1BALDH1A1MEN1KMT2A
SCHEMBL27526910 0.75 KMT2A (0.54) MTNR1AMTNR1BKMT2AKDM4EL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4554015-A THIOCARBAMATES TOYO SODA MANUFACTURING CO., LTD. (JP) 1985-11-19 US disclosed