Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | GPR3 | P46089 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 5/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13943720 | 0.82 | MAPT (0.51) | ALDH1A1ALOX15GPR3MAPTMEN1 | |
| SCHEMBL2233877 | 0.79 | ALDH1A1 (0.44) | ALDH1A1ALOX15GPR3MAPTMEN1 | |
| SCHEMBL2233882 | 0.79 | PADI4 (0.53) | ALDH1A1ALOX15GPR3MAPTMEN1 | |
| SCHEMBL2294425 | 0.77 | LIMK1 (0.53) | ALDH1A1ALOX15GPR3MAPTMEN1 | |
| SCHEMBL14139042 | 0.75 | KDM4E (0.44) | ALDH1A1ALOX15GPR3MAPTMEN1 | |
| SCHEMBL6503590 | 0.75 | GPR3 (0.55) | ALDH1A1ALOX15GPR3MAPTMEN1 | |
| SCHEMBL2469312 | 0.74 | LMNA (0.60) | ALDH1A1ALOX15MAPTMEN1KMT2A | |
| SCHEMBL28540289 | 0.71 | GPR3 (0.50) | ALDH1A1ALOX15GPR3MAPTMEN1 | |
| SCHEMBL28479943 | 0.71 | MAPT (0.52) | ALDH1A1ALOX15GPR3MAPTMEN1 | |
| SCHEMBL6829987 | 0.71 | MAPT (0.52) | ALDH1A1ALOX15GPR3MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4496679-A | USING UNSATURATED ALCOHOL, AMINE, OR MERCAPTAN | BASF AKTIENGESELLSCHAFT (DE) | 1985-01-29 | — | — | US | disclosed |