Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10949689 | 0.91 | MAOB (0.34) | ALDH1A1KDM4EL3MBTL1SMN1; SMN2MAOB | |
| SCHEMBL10952285 | 0.88 | PTGS2 (0.41) | ESR2ALDH1A1L3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL10950546 | 0.86 | L3MBTL1 (0.38) | ALDH1A1KDM4EL3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL10876558 | 0.80 | — | — | |
| SCHEMBL10950427 | 0.80 | ALDH1A1 (0.37) | ALDH1A1L3MBTL1MAOBLMNAGAA | |
| SCHEMBL10921382 | 0.79 | PTPN1 (0.39) | ALDH1A1KDM4ESMN1; SMN2MAPTLMNA | |
| SCHEMBL10879461 | 0.78 | MAPT (0.38) | ALDH1A1KDM4ESMN1; SMN2MAPTLMNA | |
| SCHEMBL10953104 | 0.76 | ALDH1A1 (0.37) | ALDH1A1KDM4EL3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL10879794 | 0.73 | LTA4H (0.39) | ALDH1A1KDM4EL3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL10949638 | 0.69 | MAPT (0.43) | ALDH1A1KDM4EL3MBTL1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4526981-A | [1,2-Dihydro-4(5)-acyl-2-oxo-2H-imidazol-4(5)-yl] methyl nitrates | MERRELL DOW PHARMACEUTICALS INC. (US) | 1985-07-02 | — | — | US | disclosed |