Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.52 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.52 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.52 |
| ▸ | FAAH | O00519 | 2/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16694791 | 0.94 | ALDH1A1 (0.53) | TRPV1 | |
| SCHEMBL16694326 | 0.94 | ALDH1A1 (0.53) | TRPV1 | |
| SCHEMBL983617 | 0.89 | THRB (0.44) | LPAR2LPAR3LPAR1 | |
| SCHEMBL17416222 | 0.89 | THRB (0.44) | LPAR2LPAR3LPAR1 | |
| SCHEMBL335169 | 0.89 | THRB (0.44) | LPAR2LPAR3LPAR1 | |
| SCHEMBL63139 | 0.89 | — | — | |
| SCHEMBL262090 | 0.89 | THRB (0.44) | LPAR2LPAR3LPAR1 | |
| SCHEMBL653851 | 0.89 | THRB (0.44) | LPAR2LPAR3LPAR1 | |
| SCHEMBL981959 | 0.89 | THRB (0.44) | LPAR2LPAR3LPAR1 | |
| SCHEMBL134759 | 0.89 | THRB (0.44) | LPAR2LPAR3LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2443130-B1 | PHOSPHONATES SYNTHONS FOR THE SYNTHESIS OF PHOSPHONATES DERIVATIVES SHOWING BETTER BIOAVAILABILITY | CENTRE NAT RECH SCIENT (FR) | 2016-08-03 | — | — | EP | claimed |
| WO-2023214017-A1 | CYCLIC CIDOFOVIR OR A PRODRUG THEREOF FOR USE IN THE TREATMENT OR PREVENTION OF AFRICAN SWINE FEVER | VIROVET NV (BE) | 2023-11-09 | — | — | WO | disclosed |
| EP-2871178-B1 | CATIONIC LIPID | KYOWA KIRIN CO LTD (JP) | 2020-12-23 | — | — | EP | disclosed |
| US-20200368173-A1 | NUCLEIC ACID-CONTAINING LIPID NANOPARTICLE | KYOWA KIRIN CO., LTD. (JP) | 2020-11-26 | — | — | US | disclosed |
| EP-3662913-A1 | NUCLEIC-ACID-CONTAINING LIPID NANOPARTICLES | Kyowa Kirin Co., Ltd. (JP) | 2020-06-10 | — | — | EP | disclosed |
| US-10342758-B2 | Cationic lipid | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2019-07-09 | — | — | US | disclosed |
| US-20180353434-A1 | NUCLEIC ACID-CONTAINING LIPID NANOPARTICLES | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2018-12-13 | — | — | US | disclosed |
| EP-3275448-A1 | NUCLEIC ACID-CONTAINING LIPID NANOPARTICLES | Kyowa Hakko Kirin Co., Ltd. (JP) | 2018-01-31 | — | — | EP | disclosed |
| US-20150174261-A1 | CATIONIC LIPID | KYOWA KIRIN CO., LTD. (JP) | 2015-06-25 | — | — | US | disclosed |
| EP-2871178-A1 | CATIONIC LIPID | Kyowa Hakko Kirin Co., Ltd. (JP) | 2015-05-13 | — | — | EP | disclosed |
| US-20090156545-A1 | Substituted Phosphate Esters of Nucleoside Phosphonates | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2009-06-18 | — | — | US | disclosed |
| US-20090005346-A1 | Azacytosine Derivatives Useful as Antiviral Agents | K.U.LEUVEN RESEARCH & DEVELOPMENT (BE) | 2009-01-01 | — | — | US | disclosed |
| WO-2008131501-A2 | NEW ANTI-VIRAL NUCLEOSIDE ANALOGS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2008-11-06 | — | — | WO | disclosed |
| WO-2008131502-A2 | ANTIVIRAL COMPOUNDS OF THE ADAMANTANE TYPE | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2008-11-06 | — | — | WO | disclosed |
| EP-1966226-A2 | AZACYTOSINE DERIVATIVES USEFUL AS ANTIVIRAL AGENTS | K.U.Leuven Research & Development (BE) | 2008-09-10 | — | — | EP | disclosed |
| EP-1866319-A1 | PHOSPHONO-PENT-2-EN-1-YL NUCLEOSIDES AND ANALOGS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-12-19 | — | — | EP | disclosed |
| WO-2007065231-A2 | AZACYTOSINE DERIVATIVES USEFUL AS ANTIVIRAL AGENTS | K.U. LEUVEN RESEARCH & DEVELOPMENT (BE) | 2007-06-14 | — | — | WO | disclosed |
| WO-2006137953-A1 | PHOSPHONO-PENT-2-EN-1-YL NUCLEOSIDES AND ANALOGS | THE REGENTS OF THE UNIVERISITY OF CALIFORNIA (US) | 2006-12-28 | — | — | WO | disclosed |
| WO-2006130217-A2 | SUBSTITUTED PHOSPHATE ESTERS OF NUCLEOSIDE PHOSPHONATES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2006-12-07 | — | — | WO | disclosed |
| WO-2006076015-A2 | 1-[2-(PHOSPHONOMETHOXY)ETHYL]-CYTOSINE AND ANALOGS THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2006-07-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156545-A1 | Substituted Phosphate Esters of Nucleoside Phosphonates | PNP, TYMP, ENPP1 | LPAR2 2121/4885LPAR3 2076/4885LPAR1 1954/4885 |
| US-20090005346-A1 | Azacytosine Derivatives Useful as Antiviral Agents | ITPA, ZC3HAV1, MTAP | LPAR2 3510/4885LPAR3 2824/4885LPAR1 2908/4885 |
| US-20180353434-A1 | NUCLEIC ACID-CONTAINING LIPID NANOPARTICLES | FASN, ABHD16A, PHAX | LPAR2 300/4885LPAR3 260/4885LPAR1 213/4885 |
| US-10342758-B2 | Cationic lipid | LIPA, LCLAT1, RNASEH1 | LPAR2 14/4885LPAR3 9/4885LPAR1 10/4885 |
| US-20150174261-A1 | CATIONIC LIPID | LIPA, LCLAT1, RNASEH1 | LPAR2 14/4885LPAR3 9/4885LPAR1 10/4885 |
| US-20200368173-A1 | NUCLEIC ACID-CONTAINING LIPID NANOPARTICLE | LIPA, LIPC, PNLIP | LPAR2 131/4885LPAR3 85/4885LPAR1 102/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.