Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP15 | Q460N3 | 1/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.46 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | IL18 | Q14116 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 2/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.38 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5783780 | 0.88 | CYP2A6 (0.48) | KDM4ELMNAALDH1A1CYP2A6CA1 | |
| SCHEMBL15109054 | 0.88 | CYP2A6 (0.48) | KDM4ELMNAALDH1A1CYP2A6CA1 | |
| SCHEMBL17907419 | 0.84 | ALDH1A1 (0.38) | MAPTMEN1LMNAPOLBMAPK1 | |
| SCHEMBL7041250 | 0.79 | PARP15 (0.63) | PARP15PARP10PARP2MAPTCYP19A1 | |
| SCHEMBL8852392 | 0.79 | PARP15 (0.63) | PARP15PARP10PARP2MAPTCYP19A1 | |
| SCHEMBL16841481 | 0.76 | TEAD4 (0.50) | MAPTMEN1LMNAPOLBMAPK1 | |
| SCHEMBL20710436 | 0.76 | LTA4H (0.52) | LMNAPGRCA1CA2CA9 | |
| SCHEMBL16705494 | 0.75 | LTA4H (0.37) | MAPTMEN1LMNARAB9AKMT2A | |
| SCHEMBL459019 | 0.74 | ALDH1A1 (0.73) | PARP15PARP10PARP2MAPTCYP19A1 | |
| SCHEMBL921496 | 0.74 | MAOA (0.56) | PARP15PARP10PARP2MAPTCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4505929-A | Sulfur-substituted diphenyl ethers having antiviral activity | THE DOW CHEMICAL COMPANY (US) | 1985-03-19 | — | — | US | disclosed |
| US-4349568-A | Sulfur-substituted diphenyl ethers having antiviral activity | THE DOW CHEMICAL COMPANY (US) | 1982-09-14 | — | — | US | disclosed |