SCHEMBL459019

SCHEMBL459019

Cc1ccc(Oc2ccc(C#N)cc2)cc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.73
CYP2A6 P11509 1/20 0.73
AR P10275 3/20 0.61
PARP15 Q460N3 1/20 0.53
PARP10 Q53GL7 1/20 0.53
PARP2 Q9UGN5 1/20 0.53
TEAD4 Q15561 1/20 0.52
POLB P06746 2/20 0.52
MAPT P10636 2/20 0.52
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
CYP19A1 P11511 2/20 0.52
KDM4E B2RXH2 1/20 0.52
LMNA P02545 1/20 0.52
PKM P14618 1/20 0.52
MAPK1 P28482 1/20 0.52
RAB9A P51151 1/20 0.52
IL18 Q14116 1/20 0.52
TDP1 Q9NUW8 1/20 0.50
SLC6A4 P31645 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31070291 0.94 ALDH1A1 (0.64) ALDH1A1CYP2A6ARPARP15PARP10
P-Cresol SCHEMBL29176413 0.90 ALDH1A1 (0.59) ALDH1A1CYP2A6ARPARP15PARP10
SCHEMBL8852392 0.88 PARP15 (0.63) ALDH1A1CYP2A6ARPARP15PARP10
SCHEMBL7041250 0.88 PARP15 (0.63) ALDH1A1CYP2A6ARPARP15PARP10
SCHEMBL22724763 0.86 ALDH1A1 (0.59) ALDH1A1CYP2A6ARPARP15PARP10
SCHEMBL8544256 0.85 ALDH1A1 (0.53) ALDH1A1CYP2A6ARPARP15PARP10
P-Xylene SCHEMBL3926102 0.85 CYP2A6 (1.00) ALDH1A1CYP2A6ARKMT2ATDP1
SCHEMBL921658 0.85 ALDH1A1 (0.59) ALDH1A1CYP2A6ARPARP15PARP10
SCHEMBL46818 0.85
SCHEMBL27329500 0.85 CYP2A6 (1.00) ALDH1A1CYP2A6ARKMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114560780-A Method for preparing 4- (4-methylphenoxy) benzylamine by using modified nano nickel as catalyst 南京科力硕生物科技有限公司 2022-05-31 CN claimed
CN-105294493-A Synthetic method of 4-(4-methylphenoxy)benzonitrile WANG XIAOWEI 2016-02-03 CN claimed
CN-102863356-B Preparation method for 4-(4-methylphenoxy)cyanobenzene CHANGZHOU HUANAN CHEMICAL INDUSTRY CO., LTD. (CN) 2014-10-15 CN claimed
CN-102863356-A Preparation method for 4-(4-methylphenoxy)cyanobenzene CHANGZHOU HUANAN CHEMICAL CO LTD 2013-01-09 CN claimed
JP-8291116-A None JP disclosed
CN-121347691-A Analysis method for 4- (4-methylphenoxy) benzonitrile content 山东京博农化科技股份有限公司 2026-01-16 CN disclosed
CN-121347691-A Analysis method for 4- (4-methylphenoxy) benzonitrile content 山东京博农化科技股份有限公司 2026-01-16 CN disclosed
CN-121226171-A Synthesis method of 4- (4-methylphenoxy) benzylamine salt 江西汇和化工有限公司 2025-12-30 CN disclosed
CN-121135605-A Synthesis method of 4- (4-methylphenoxy) benzonitrile 江西汇和化工有限公司 2025-12-16 CN disclosed
CN-121135605-A Synthesis method of 4- (4-methylphenoxy) benzonitrile 江西汇和化工有限公司 2025-12-16 CN disclosed
CN-118359503-A Synthesis method of copper-catalyzed diaryl ether promoted by visible light 新疆大学 2024-07-19 CN disclosed
CN-118359540-A Method for producing tolfenpyrad insecticide 新沂市永诚化工有限公司 2024-07-19 CN disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed
US-20100166655-A1 1, 4-DISUBSTITUTED 3-CYANO-PYRIDONE DERIVATIVES AND THEIR USE AS POSITIVE ALLOSTERIC MODULATORS OF MGLUR2-RECEPTORS JANSSEN PHARMACEUTICA N.V. (BE) 2010-07-01 US disclosed
US-20100166655-A1 1, 4-DISUBSTITUTED 3-CYANO-PYRIDONE DERIVATIVES AND THEIR USE AS POSITIVE ALLOSTERIC MODULATORS OF MGLUR2-RECEPTORS JANSSEN PHARMACEUTICA N.V. (BE) 2010-07-01 US disclosed
WO-2009117421-A2 HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE KALYPSYS, INC. (US) 2009-09-24 WO disclosed
WO-2009117421-A2 HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE KALYPSYS, INC. (US) 2009-09-24 WO disclosed
WO-2009107764-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS 住友化学株式会社 (JP) 2009-09-03 WO disclosed
JP-H08291116-A PRODUCTION OF 4-(4-ALKYLPHENOXY)BENZYLAMINES MITSUBISHI CHEM CORP 1996-11-05 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 ALDH1A1 2743/4885CYP2A6 3797/4885AR 4285/4885
US-20100166655-A1 1, 4-DISUBSTITUTED 3-CYANO-PYRIDONE DERIVATIVES AND THEIR USE AS POSITIVE ALLOSTERIC MODULATORS OF MGLUR2-RECEPTORS GRM2, GRM1, GRM3 ALDH1A1 2815/4885CYP2A6 1213/4885AR 2811/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.