Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.41 |
| ▸ | GFER | P55789 | 2/20 | 0.40 |
| ▸ | AXL | P30530 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | INSR | P06213 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12373172 | 0.80 | CYP2A6 (0.42) | CYP2A6KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL4533808 | 0.79 | SMN1; SMN2 (0.56) | KDM4EMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL2275595 | 0.79 | RAB9A (0.56) | GFERAXLKDM4EKMT2AALDH1A1 | |
| SCHEMBL8170041 | 0.79 | KMT2A (0.47) | CYP2A6KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL12566875 | 0.76 | INSR (0.42) | CYP2A6KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL9255622 | 0.75 | GFER (0.66) | GFERAXLKDM4EMEN1KMT2A | |
| SCHEMBL25500478 | 0.75 | NPC1 (0.41) | CYP2A6INSRRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL14858956 | 0.75 | KEAP1 (0.59) | KDM4EMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL13462724 | 0.75 | NPC1 (0.58) | CYP2A6KMT2AALDH1A1MAPK1TSHR | |
| SCHEMBL12967447 | 0.73 | KDM4E (0.61) | GFERKDM4EMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4544738-A | FIBER-REACTIVE YELLOW AND ORANGE DYES | BASF AKTIENGESELLSCHAFT (DE) | 1985-10-01 | — | — | US | disclosed |