Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TTR | P02766 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11460057 | 0.88 | PRMT6 (0.38) | PRMT6L3MBTL1 | |
| SCHEMBL10957232 | 0.79 | PRMT6 (0.59) | PRMT6APEX1 | |
| SCHEMBL11247841 | 0.78 | PRMT6 (0.39) | PRMT6APEX1 | |
| SCHEMBL11258973 | 0.75 | APEX1 (0.32) | APEX1 | |
| SCHEMBL11253646 | 0.74 | PRMT6 (0.38) | PRMT6APEX1L3MBTL1 | |
| SCHEMBL10741444 | 0.74 | PRMT6 (0.61) | PRMT6 | |
| SCHEMBL10959685 | 0.73 | PRMT6 (0.59) | PRMT6 | |
| SCHEMBL11252903 | 0.72 | APEX1 (0.46) | PRMT6APEX1L3MBTL1TTR | |
| SCHEMBL11238704 | 0.71 | ACHE (0.59) | APEX1 | |
| SCHEMBL11479765 | 0.71 | PRMT6 (0.42) | PRMT6L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0001699-B1 | DERIVATIVES OF FURYL COMPOUNDS, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLAXO GROUP LIMITED (GB) | 1982-02-24 | — | — | EP | disclosed |
| US-4288443-A | HISTAMINE ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 1981-09-08 | — | — | US | disclosed |
| EP-0001699-A2 | Derivatives of furyl compounds, their preparation and pharmaceutical compositions containing them | GLAXO GROUP LIMITED (GB) | 1979-05-02 | — | — | EP | disclosed |