Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 1/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.44 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CDK4 | P11802 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10922113 | 0.82 | HTR6 (0.40) | IMPDH2MTNR1AMTNR1BHPGDALDH1A1 | |
| SCHEMBL5785504 | 0.78 | SSTR3 (0.60) | MTNR1AMTNR1BALDH1A1KDM4ENPC1 | |
| SCHEMBL2002472 | 0.78 | HPGD (0.50) | IMPDH2HPGDALDH1A1KDM4EMEN1 | |
| SCHEMBL10919830 | 0.76 | MTNR1A (0.47) | MTNR1AMTNR1BALDH1A1KDM4EMEN1 | |
| SCHEMBL10919619 | 0.73 | BCHE (0.56) | MTNR1AMTNR1B | |
| SCHEMBL10918935 | 0.72 | MTNR1A (0.41) | MTNR1AMTNR1BALDH1A1KDM4EMEN1 | |
| SCHEMBL10918951 | 0.71 | LOXL2 (0.49) | MTNR1AMTNR1BALDH1A1KDM4EMEN1 | |
| SCHEMBL10910311 | 0.71 | MEN1 (0.42) | MTNR1AMTNR1BMEN1KMT2ALMNA | |
| SCHEMBL2004601 | 0.71 | MEN1 (0.56) | MTNR1AMTNR1BHPGDALDH1A1KDM4E | |
| SCHEMBL3817884 | 0.70 | CA2 (0.70) | MTNR1AHPGDALDH1A1MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0076713-B1 | AMINOMETHYL-1H-INDOLE-4-METHANOL DERIVATIVES AND THEIR SALTS, PROCESS AND INTERMEDIATES FOR THEIR PREPARATION, THEIR USE AS MEDICINES AND COMPOSITIONS CONTAINING THEM | ROUSSEL-UCLAF (FR) | 1986-01-08 | — | — | EP | disclosed |