Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | EP300 | Q09472 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31525908 | 0.85 | PKM (0.58) | SLC2A1CA7ALDH1A1TSHRGAA | |
| SCHEMBL10640095 | 0.85 | PKM (0.58) | SLC2A1CA7ALDH1A1TSHRGAA | |
| SCHEMBL10568117 | 0.84 | HTR2C (0.56) | SMN1; SMN2CA7TSHR | |
| SCHEMBL10575175 | 0.84 | TRPV4 (0.50) | SMN1; SMN2SLC2A1CA7ALDH1A1TSHR | |
| SCHEMBL29652427 | 0.84 | TRPV4 (0.50) | SMN1; SMN2SLC2A1CA7ALDH1A1TSHR | |
| SCHEMBL31172537 | 0.84 | PKM (0.56) | SMN1; SMN2SLC2A1CA7ALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL10350988 | 0.83 | MAOA (0.56) | SMN1; SMN2CA7TSHRGAAMAPT | |
| Hydrochloric Acid SCHEMBL10350486 | 0.83 | HTR2C (0.54) | SMN1; SMN2SLC2A1CA7 | |
| SCHEMBL10641792 | 0.80 | TRPV4 (0.50) | SMN1; SMN2SLC2A1CA7ALDH1A1TSHR | |
| SCHEMBL10350544 | 0.78 | CA7 (0.45) | SMN1; SMN2CA7ALDH1A1GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230174522-A1 | Benzisoxazole Sulfonamide Derivatives | MONASH UNIVERSITY (AU) | 2023-06-08 | — | — | US | disclosed |
| US-20200399258-A1 | Benzisoxazole Sulfonamide Derivatives | PFIZER INC. | 2020-12-24 | — | — | US | disclosed |
| EP-0088346-B1 | 2-AMINOMETHYL-PHENOL DERIVATIVES, PROCESS FOR THEIR PREPARATION, THEIR USE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-06-05 | — | — | EP | disclosed |
| EP-0088346-A2 | 2-Aminomethyl-phenol derivatives, process for their preparation, their use and pharmaceutical compositions containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-09-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200399258-A1 | Benzisoxazole Sulfonamide Derivatives | BRIX1, RB1, BCR | SMN1; SMN2 860/4885SLC2A1 3093/4885CA7 659/4885 |
| US-20230174522-A1 | Benzisoxazole Sulfonamide Derivatives | BRIX1, RB1, BCR | SMN1; SMN2 941/4885SLC2A1 3248/4885CA7 629/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.