Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 7/20 | 0.35 |
| ▸ | PTPN2 | P17706 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | PTPRB | P23467 | 3/20 | 0.32 |
| ▸ | PTPN6 | P29350 | 3/20 | 0.32 |
| ▸ | PTPRC | P08575 | 2/20 | 0.32 |
| ▸ | PTPRE | P23469 | 2/20 | 0.32 |
| ▸ | THRA | P10827 | 2/20 | 0.31 |
| ▸ | THRB | P10828 | 2/20 | 0.31 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10967347 | 0.97 | PTPN1 (0.35) | PTPN1PTPN2MAPTTP53PTPRB | |
| SCHEMBL10962652 | 0.75 | PTPN1 (0.35) | PTPN1PTPN2MAPTTP53PTPRB | |
| Water SCHEMBL10889889 | 0.74 | PTPN1 (0.34) | PTPN1PTPN2MAPTTP53GPR35 | |
| SCHEMBL10967884 | 0.73 | PTPN1 (0.35) | PTPN1PTPN2MAPTTP53PTPRB | |
| SCHEMBL10888902 | 0.73 | PARP1 (0.34) | — | |
| SCHEMBL10891351 | 0.70 | NOS3 (0.34) | MAPTTP53MEN1KMT2ANPC1 | |
| SCHEMBL10967367 | 0.69 | GPR35 (0.45) | PTPN1PTPN2MAPTTP53GPR35 | |
| SCHEMBL10894281 | 0.67 | PKM (0.54) | PTPN1PTPN2MAPTGPR35NPC1 | |
| SCHEMBL10963524 | 0.67 | MAPT (0.46) | PTPN1PTPN2MAPTTP53THRB | |
| SCHEMBL10963320 | 0.66 | KEAP1 (0.49) | PTPN1MAPTTP53GPR35KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0159964-A2 | 3-Substituted thiopyrone | CIBA-GEIGY AG (CH) | 1985-10-30 | — | — | EP | claimed |
| EP-0159964-A2 | 3-Substituted thiopyrone | CIBA-GEIGY AG (CH) | 1985-10-30 | — | — | EP | disclosed |