Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XPO1 | O14980 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | RGS4 | P49798 | 1/20 | 0.32 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.32 |
| ▸ | PIN4 | Q9Y237 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | RGS12 | O14924 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2464170 | 0.85 | KDM4E (0.43) | ALDH1A1LMNAMAPTBLMNPSR1 | |
| SCHEMBL11805906 | 0.83 | XPO1 (0.33) | XPO1ALDH1A1LMNAGMNNMAPT | |
| SCHEMBL4395914 | 0.83 | MGLL (0.33) | XPO1ALDH1A1LMNAGMNNMAPT | |
| SCHEMBL4256829 | 0.81 | KDM4E (0.46) | ALDH1A1LMNAMAPTNPSR1MGLL | |
| SCHEMBL4011867 | 0.81 | ALDH1A1 (0.48) | XPO1ALDH1A1LMNAGMNNMAPT | |
| SCHEMBL22105296 | 0.80 | JUN (0.34) | XPO1FOSJUNNFKB1NFKB2 | |
| SCHEMBL22403738 | 0.79 | XPO1 (0.32) | XPO1ALDH1A1LMNAGMNNMAPT | |
| SCHEMBL6881981 | 0.79 | RGS4 (0.32) | XPO1ALDH1A1LMNAGMNNMAPT | |
| SCHEMBL8883684 | 0.79 | MGLL (0.46) | ALDH1A1LMNAMAPTNPSR1MGLL | |
| SCHEMBL8885500 | 0.79 | MGLL (0.41) | ALDH1A1LMNAMAPTNPSR1MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4556651-A | Secalonic acid derivatives as antitumor agents | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1985-12-03 | — | — | US | disclosed |
| EP-0064199-B1 | NOVEL SECALONIC ACID DERIVATIVES AND METHOD FOR PREPARING THEREOF | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1985-08-21 | — | — | EP | disclosed |
| US-4418061-A | ANTITUMOR AGENTS | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1983-11-29 | — | — | US | disclosed |
| EP-0064199-A1 | Novel secalonic acid derivatives and method for preparing thereof | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1982-11-10 | — | — | EP | disclosed |