Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RGS4 | P49798 | 2/20 | 0.32 |
| ▸ | XPO1 | O14980 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4395914 | 0.81 | MGLL (0.33) | RGS4XPO1ALDH1A1GMNNLMNA | |
| SCHEMBL11805906 | 0.81 | XPO1 (0.33) | RGS4XPO1ALDH1A1GMNNLMNA | |
| SCHEMBL4011867 | 0.79 | ALDH1A1 (0.48) | RGS4XPO1ALDH1A1GMNNLMNA | |
| SCHEMBL8883684 | 0.77 | MGLL (0.46) | ALDH1A1LMNAMAPTNPSR1MGLL | |
| SCHEMBL8885500 | 0.77 | MGLL (0.41) | ALDH1A1LMNAMAPTNPSR1MGLL | |
| SCHEMBL8443692 | 0.77 | CASP3 (0.44) | ALDH1A1MAPTNPSR1 | |
| SCHEMBL8443620 | 0.76 | MGLL (0.48) | ALDH1A1LMNAMAPTNPSR1MGLL | |
| SCHEMBL2786847 | 0.76 | PTGS1 (0.36) | ALDH1A1GMNNLMNAMAPTTHPO | |
| SCHEMBL8885012 | 0.76 | MGLL (0.48) | ALDH1A1LMNAMAPTNPSR1MGLL | |
| SCHEMBL907802 | 0.76 | MGLL (0.48) | ALDH1A1LMNAMAPTNPSR1MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10093762-B2 | Process for modifying polymers | AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) | 2018-10-09 | — | — | US | claimed |
| US-20180155480-A1 | PROCESS FOR MODIFYING POLYMERS | WILMINGTON TRUST (LONDON) LIMITED, AS COLLATERAL AGENT (GB) | 2018-06-07 | — | — | US | claimed |
| EP-3286253-A1 | PROCESS FOR MODIFYING POLYMERS | Akzo Nobel Chemicals International B.V. (NL) | 2018-02-28 | — | — | EP | claimed |
| US-9688783-B2 | Process for modifying ethylene-based polymers and copolymers | AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) | 2017-06-27 | — | — | US | claimed |
| US-20160347876-A1 | Process for Modifying Ethylene-Based Polymers and Copolymers | WILMINGTON TRUST (LONDON) LIMITED, AS COLLATERAL AGENT (GB) | 2016-12-01 | — | — | US | claimed |
| WO-2016170018-A1 | PROCESS FOR MODIFYING POLYMERS | AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) | 2016-10-27 | — | — | WO | claimed |
| US-20040241706-A1 | Highly specific modulators of GTPases for target validation | IRM, LLC | 2004-12-02 | — | — | US | claimed |
| WO-2004024082-A2 | HIGHLY SPECIFIC MODULATORS OF GTPASES FOR TARGET VALIDATION | IRM, LLC (GB) | 2004-03-25 | — | — | WO | claimed |
| US-10093762-B2 | Process for modifying polymers | AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) | 2018-10-09 | — | — | US | disclosed |
| US-20180155480-A1 | PROCESS FOR MODIFYING POLYMERS | WILMINGTON TRUST (LONDON) LIMITED, AS COLLATERAL AGENT (GB) | 2018-06-07 | — | — | US | disclosed |
| US-20180086887-A1 | PROCESS FOR CROSSLINKING POLYPROPYLENE | WILMINGTON TRUST (LONDON) LIMITED, AS COLLATERAL AGENT (GB) | 2018-03-29 | — | — | US | disclosed |
| EP-3286253-A1 | PROCESS FOR MODIFYING POLYMERS | Akzo Nobel Chemicals International B.V. (NL) | 2018-02-28 | — | — | EP | disclosed |
| US-9688783-B2 | Process for modifying ethylene-based polymers and copolymers | AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) | 2017-06-27 | — | — | US | disclosed |
| US-20160347876-A1 | Process for Modifying Ethylene-Based Polymers and Copolymers | WILMINGTON TRUST (LONDON) LIMITED, AS COLLATERAL AGENT (GB) | 2016-12-01 | — | — | US | disclosed |
| WO-2016170018-A1 | PROCESS FOR MODIFYING POLYMERS | AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) | 2016-10-27 | — | — | WO | disclosed |
| EP-3066151-A1 | PROCESS FOR MODIFYING ETHYLENE-BASED POLYMERS AND COPOLYMERS | Akzo Nobel Chemicals International B.V. (NL) | 2016-09-14 | — | — | EP | disclosed |
| WO-2015067533-A1 | PROCESS FOR MODIFYING ETHYLENE-BASED POLYMERS AND COPOLYMERS | AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) | 2015-05-14 | — | — | WO | disclosed |
| US-20040241706-A1 | Highly specific modulators of GTPases for target validation | IRM, LLC | 2004-12-02 | — | — | US | disclosed |
| WO-2004024082-A2 | HIGHLY SPECIFIC MODULATORS OF GTPASES FOR TARGET VALIDATION | IRM, LLC (GB) | 2004-03-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040241706-A1 | Highly specific modulators of GTPases for target validation | CDC42, ARHGDIB, ARHGEF2 | RGS4 94/4885XPO1 1839/4885ALDH1A1 4883/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.