Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.46 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.46 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.46 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HCAR2 | Q8TDS4 | 8/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3915266 | 0.77 | DHODH (0.77) | CASP3SENP7DHODHMAPTGAA | |
| SCHEMBL1415624 | 0.76 | CASP3 (0.45) | CASP3SENP7DHODHMAPK14MAPK13 | |
| SCHEMBL10803715 | 0.75 | MAPT (0.50) | CASP3DHODHALDH1A1HSD17B10TSHR | |
| SCHEMBL11409753 | 0.72 | ALDH1A1 (0.38) | DHODHALDH1A1HSD17B10ALOX15TSHR | |
| SCHEMBL8022715 | 0.72 | MAPT (0.50) | CASP3DHODHALDH1A1HSD17B10TSHR | |
| SCHEMBL9130763 | 0.72 | MAPK13 (0.50) | MAPK14MAPK13MAPK12MAPK11MAPT | |
| Diphenylamine SCHEMBL8119680 | 0.72 | HSD17B10 (0.80) | CASP3SENP7MAPK14MAPK13MAPK12 | |
| Diphenylamine SCHEMBL27671770 | 0.72 | HSD17B10 (0.80) | CASP3SENP7MAPK14MAPK13MAPK12 | |
| Diphenylamine SCHEMBL1691353 | 0.72 | HSD17B10 (0.80) | CASP3SENP7MAPK14MAPK13MAPK12 | |
| Diphenylamine SCHEMBL27851138 | 0.72 | HSD17B10 (0.80) | CASP3SENP7MAPK14MAPK13MAPK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0028445-B1 | ACRIDINONES, THEIR PREPARATION AND USE; INTERMEDIATES AND THEIR PREPARATION | CIBA-GEIGY AG (CH) | 1985-10-23 | — | — | EP | claimed |
| EP-0028445-B1 | ACRIDINONES, THEIR PREPARATION AND USE; INTERMEDIATES AND THEIR PREPARATION | CIBA-GEIGY AG (CH) | 1985-10-23 | — | — | EP | disclosed |
| EP-0028445-A2 | Acridinones, their preparation and use; intermediates and their preparation | CIBA-GEIGY AG (CH) | 1981-05-13 | — | — | EP | disclosed |
| US-4258190-A | BY REACTING CYCLOHEXANONE AND AN OXALATE ESTER TO FORM A CYCLOHEXANONECARBOXYLATE INTERMEDIATE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-03-24 | — | — | US | disclosed |