Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.38 |
| ▸ | MEN1 | O00255 | 6/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 7/20 | 0.36 |
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10964731 | 0.72 | CASP3 (0.47) | ALDH1A1KMT2AMEN1HSD17B10GAA | |
| SCHEMBL11412314 | 0.69 | NPC1 (0.31) | SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL8022715 | 0.69 | MAPT (0.50) | ALDH1A1KMT2AMEN1HSD17B10GAA | |
| SCHEMBL9130763 | 0.69 | MAPK13 (0.50) | KMT2AMEN1GAAMAPTSMN1; SMN2 | |
| Diphenylamine SCHEMBL14693877 | 0.66 | HSD17B10 (0.60) | ALDH1A1KMT2AMEN1CYP1A2CYP2C19 | |
| SCHEMBL21899483 | 0.64 | HPGD (0.45) | ALDH1A1KMT2AMEN1CYP1A2CYP2C19 | |
| SCHEMBL1828521 | 0.64 | HSD17B10 (0.55) | ALDH1A1KMT2AMEN1CYP1A2CYP2C19 | |
| SCHEMBL11411153 | 0.63 | ALDH1A1 (0.36) | ALDH1A1KMT2AMEN1GAAMAPT | |
| Diphenylamine SCHEMBL8119680 | 0.62 | HSD17B10 (0.80) | ALDH1A1KMT2AMEN1CYP1A2CYP2C19 | |
| Diphenylamine SCHEMBL1691353 | 0.62 | HSD17B10 (0.80) | ALDH1A1KMT2AMEN1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4199598-A | USE OF 2-AMINO-CYCLOPENT-1-ENE-1-DITHIOCARBOXYLIC ACIDS | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1980-04-22 | — | — | US | claimed |
| US-4199598-A | USE OF 2-AMINO-CYCLOPENT-1-ENE-1-DITHIOCARBOXYLIC ACIDS | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1980-04-22 | — | — | US | disclosed |
| US-4179463-A | ADRENERGIC BLOCKING AGENTS, DOPAMINE-B-HYDROXYLASE INHIBITORS | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1979-12-18 | — | — | US | disclosed |