Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 17/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 17/20 | 0.44 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL369410 | 0.69 | CCNA2 (0.40) | EGLN1CSNK2A1 | |
| SCHEMBL10968821 | 0.69 | PDE3B (0.40) | PDE3BPDE3A | |
| SCHEMBL15388981 | 0.68 | PARP1 (0.51) | PDE3BPDE3APARP1 | |
| SCHEMBL10917620 | 0.66 | MAPK1 (0.44) | PDE3BPDE3ACSNK2A1 | |
| SCHEMBL4159209 | 0.65 | ALDH1A1 (0.39) | PDE3BPDE3A | |
| SCHEMBL8627138 | 0.65 | LMNA (0.39) | EGLN1PARP1 | |
| SCHEMBL5004845 | 0.64 | CCR1 (0.50) | — | |
| SCHEMBL16736421 | 0.63 | CA12 (0.55) | PDE3BPDE3A | |
| SCHEMBL2957821 | 0.63 | F11 (0.46) | PDE3BPDE3A | |
| SCHEMBL30577499 | 0.63 | PARP1 (0.54) | CSNK2A1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0154190-A1 | Pyridones | MERCK PATENT GmbH (DE) | 1985-09-11 | — | — | EP | disclosed |