Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.38 |
| ▸ | NOS1 | P29475 | 7/20 | 0.38 |
| ▸ | AXL | P30530 | 2/20 | 0.38 |
| ▸ | MELK | Q14680 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | METAP2 | P50579 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12321248 | 0.71 | NOS1 (0.56) | CCNA2CDK2CCNA1NOS1AXL | |
| SCHEMBL5160632 | 0.71 | ALDH1A1 (0.46) | MELKEGLN1ALDH1A1KDM4ERAB9A | |
| SCHEMBL10967425 | 0.69 | PDE3B (0.44) | EGLN1CSNK2A1 | |
| SCHEMBL15168259 | 0.69 | QPCT (0.43) | CCNA2CDK2CCNA1NOS1AXL | |
| SCHEMBL8983079 | 0.68 | LMNA (0.47) | CCNA2CDK2CCNA1MKNK1NOS1 | |
| SCHEMBL9440567 | 0.67 | KDM4E (0.36) | ALDH1A1JAK2KDM4EGAAMAPT | |
| SCHEMBL8627138 | 0.67 | LMNA (0.39) | MELKEGLN1ALDH1A1KDM4EMEN1 | |
| SCHEMBL26462921 | 0.66 | CDK2 (0.35) | CCNA2CDK2CCNA1NOS1AXL | |
| SCHEMBL29772171 | 0.66 | EGLN1 (0.34) | EGLN1ALDH1A1 | |
| SCHEMBL359265 | 0.64 | GRM4 (0.43) | CDK2METAP2ALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007510-A1 | COMPOUNDS FOR BINDING AND IMAGING AMYLOID PLAQUES AND THEIR USE | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-01-19 | — | — | WO | disclosed |