Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10977724 | 0.98 | CYP3A4 (0.39) | ALOX15CYP3A4HSD17B10KDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL10978246 | 0.98 | CYP3A4 (0.39) | ALOX15CYP3A4HSD17B10KDM4EMEN1 | |
| SCHEMBL10969178 | 0.86 | ALDH1A1 (0.38) | ALOX15HSD17B10KDM4EMEN1GAA | |
| Hydrochloric Acid SCHEMBL10974604 | 0.84 | ALDH1A1 (0.37) | ALOX15HSD17B10KDM4EMEN1GAA | |
| SCHEMBL9421173 | 0.83 | PTGS1 (0.37) | ALOX15HSD17B10KDM4EMEN1POLB | |
| Bromide SCHEMBL11354189 | 0.77 | ACHE (0.39) | ALOX15CYP3A4HSD17B10KDM4EMEN1 | |
| Bromide SCHEMBL11356265 | 0.77 | SELL (0.31) | — | |
| SCHEMBL5154750 | 0.75 | TDP1 (0.41) | CYP3A4KDM4EMEN1MAPTRAB9A | |
| SCHEMBL5153906 | 0.75 | LMNA (0.33) | HSD17B10MAPT | |
| Hydrochloric Acid SCHEMBL10884932 | 0.74 | TDP1 (0.39) | CYP3A4KDM4EMEN1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0086126-B1 | IMIDAZOLINE DERIVATIVES, THEIR PREPARATION AND THERAPEUTICAL APPLICATION | SYNTHELABO (FR) | 1985-07-24 | — | — | EP | claimed |
| US-4492709-A | VISION DEFECTX | SYNTHELABO (FR) | 1985-01-08 | — | — | US | disclosed |