Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 7/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10974604 | 0.98 | ALDH1A1 (0.37) | ALDH1A1HSD17B10ALOX15ALOX12HPGD | |
| SCHEMBL10967741 | 0.86 | ALOX15 (0.41) | HSD17B10ALOX15GAAMAPTMEN1 | |
| Hydrochloric Acid SCHEMBL10978246 | 0.84 | CYP3A4 (0.39) | HSD17B10ALOX15GAAMAPTMEN1 | |
| Hydrochloric Acid SCHEMBL10977724 | 0.84 | CYP3A4 (0.39) | HSD17B10ALOX15GAAMAPTMEN1 | |
| SCHEMBL9421173 | 0.83 | PTGS1 (0.37) | ALDH1A1HSD17B10ALOX15HPGDSMN1; SMN2 | |
| SCHEMBL5153906 | 0.79 | LMNA (0.33) | HSD17B10MAPTLMNATDP1 | |
| SCHEMBL5154750 | 0.79 | TDP1 (0.41) | ALDH1A1SMN1; SMN2MAPK1MAPTMEN1 | |
| Bromide SCHEMBL11354245 | 0.77 | PTGS1 (0.41) | ALDH1A1HSD17B10ALOX15ALOX12HPGD | |
| Hydrochloric Acid SCHEMBL10884932 | 0.77 | TDP1 (0.39) | ALDH1A1MAPK1MAPTMEN1KMT2A | |
| Bromide SCHEMBL11354189 | 0.74 | ACHE (0.39) | ALDH1A1HSD17B10ALOX15ALOX12HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0086126-B1 | IMIDAZOLINE DERIVATIVES, THEIR PREPARATION AND THERAPEUTICAL APPLICATION | SYNTHELABO (FR) | 1985-07-24 | — | — | EP | claimed |
| US-4492709-A | VISION DEFECTX | SYNTHELABO (FR) | 1985-01-08 | — | — | US | disclosed |