Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SELL | P14151 | 1/20 | 0.31 |
| ▸ | SELP | P16109 | 1/20 | 0.31 |
| ▸ | SELE | P16581 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9421173 | 0.82 | PTGS1 (0.37) | — | |
| Bromide SCHEMBL11354612 | 0.81 | BACE1 (0.35) | — | |
| Bromide SCHEMBL11354189 | 0.80 | ACHE (0.39) | — | |
| SCHEMBL10967741 | 0.77 | ALOX15 (0.41) | — | |
| Bromide SCHEMBL11354245 | 0.76 | PTGS1 (0.41) | — | |
| Hydrochloric Acid SCHEMBL10978246 | 0.76 | CYP3A4 (0.39) | — | |
| Hydrochloric Acid SCHEMBL10977724 | 0.76 | CYP3A4 (0.39) | — | |
| SCHEMBL9577811 | 0.74 | S100B (0.39) | — | |
| SCHEMBL10969178 | 0.73 | ALDH1A1 (0.38) | — | |
| Hydrochloric Acid SCHEMBL10974740 | 0.72 | CA12 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4250186-A | ADMINISTERING A 2-(SUBSTITUTED PHENYL-IMINO)-IMIDAZOLIDINE COMPOUND | BOEHRINGER INGELHEIM GMBH (DE) | 1981-02-10 | — | — | US | disclosed |