Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.58 |
| ▸ | CNR1 | P21554 | 7/20 | 0.52 |
| ▸ | HTR6 | P50406 | 4/20 | 0.51 |
| ▸ | CCR2 | P41597 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 4/20 | 0.48 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.47 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.47 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.47 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18019294 | 0.84 | KIF18A (0.45) | KIF18ACNR1HTR6CCR2LMNA | |
| SCHEMBL25020313 | 0.83 | CCR2 (0.51) | KIF18ACNR1CCR2CNR2NAMPT | |
| SCHEMBL2462163 | 0.81 | KIF18A (0.61) | KIF18AHTR6CNR2ABCC9ABCC8 | |
| SCHEMBL776300 | 0.81 | HTR2A (0.54) | HTR6ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL2350373 | 0.79 | AKR1B1 (0.51) | KIF18AHTR6ABCC9ABCC8KCNJ11 | |
| SCHEMBL8866862 | 0.79 | HTR6 (0.52) | CNR1HTR6ABCC9ABCC8KCNJ11 | |
| SCHEMBL5258855 | 0.79 | HTR6 (0.61) | KIF18ACNR1HTR6CCR2CNR2 | |
| (Phenylsulfonyl)Benzene SCHEMBL4674390 | 0.79 | HTR6 (0.50) | KIF18AHTR6LMNAPKMCYP2C9 | |
| SCHEMBL228959 | 0.78 | KIF18A (0.57) | KIF18AHTR6CNR2CYP2C9 | |
| SCHEMBL227808 | 0.78 | KIF18A (0.57) | KIF18AHTR6CNR2LMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4554381-A | BORON TRIFLUORIDE, HYDROFLUORIC ACID | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1985-11-19 | — | — | US | disclosed |