Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TYR | P14679 | 2/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6584398 | 0.83 | ALOX15 (0.51) | ALDH1A1LMNAALOX15HSD17B10TYR | |
| SCHEMBL9513810 | 0.83 | ALOX15 (0.51) | ALDH1A1LMNAALOX15HSD17B10TYR | |
| SCHEMBL27535126 | 0.83 | ALOX15 (0.51) | ALDH1A1LMNAALOX15HSD17B10TYR | |
| SCHEMBL19720241 | 0.81 | EGFR (0.38) | ALDH1A1LMNAALOX15HSD17B10TYR | |
| SCHEMBL27607478 | 0.79 | RXRA (0.38) | ALDH1A1LMNAALOX15HSD17B10SLC7A5 | |
| SCHEMBL7464405 | 0.77 | SLC7A5 (0.57) | SLC7A5BLM | |
| SCHEMBL630703 | 0.77 | SLC7A5 (0.57) | SLC7A5BLM | |
| SCHEMBL594571 | 0.77 | SLC7A5 (0.57) | SLC7A5BLM | |
| SCHEMBL23544355 | 0.77 | SLC7A5 (0.38) | LMNANR1I2SLC7A5BLMKMT2A | |
| SCHEMBL29286178 | 0.77 | SLC7A5 (0.38) | LMNANR1I2SLC7A5BLMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0048763-B1 | SULFUR-CONTAINING ACYLAMINO ACIDS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1985-11-06 | — | — | EP | disclosed |
| US-4425333-A | HYPOTENSIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1984-01-10 | — | — | US | disclosed |
| EP-0048763-A1 | SULFUR-CONTAINING ACYLAMINO ACIDS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1982-04-07 | — | — | EP | disclosed |