Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 3/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27589632 | 0.82 | RXRA (0.39) | RXRANR1H2NR1H3POLBALDH1A1 | |
| SCHEMBL19720241 | 0.79 | EGFR (0.38) | LTA4HSLC7A5KDM4EALDH1A1LMNA | |
| SCHEMBL10972221 | 0.79 | ALDH1A1 (0.39) | LTA4HSLC7A5KDM4EALDH1A1LMNA | |
| SCHEMBL5561516 | 0.75 | RXFP1 (0.47) | RXRANR1H2LTA4HNR1H3SLC7A5 | |
| SCHEMBL5560898 | 0.74 | RXFP1 (0.49) | RXRANR1H2LTA4HNR1H3POLB | |
| SCHEMBL10626720 | 0.73 | ESR1 (0.39) | SLC7A5KDM4EALDH1A1LMNACYP3A4 | |
| SCHEMBL7464405 | 0.72 | SLC7A5 (0.57) | SLC7A5BLM | |
| SCHEMBL630703 | 0.72 | SLC7A5 (0.57) | SLC7A5BLM | |
| SCHEMBL594571 | 0.72 | SLC7A5 (0.57) | SLC7A5BLM | |
| SCHEMBL23544355 | 0.72 | SLC7A5 (0.38) | LTA4HSLC7A5LMNABLMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1578659-A | Modulators of peroxisome proliferator activated receptors (ppar) | LILLY CO ELI (US) | 2005-02-09 | — | — | CN | disclosed |