SCHEMBL10974469

SCHEMBL10974469

O=C(Nc1ccccc1)C(Br)(Br)Br

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.58
EPHX1 P07099 1/20 0.58
TSHR P16473 1/20 0.58
EPHX2 P34913 1/20 0.58
CDK9 P50750 1/20 0.58
SMN1; SMN2 Q16637 1/20 0.58
CLK4 Q9HAZ1 1/20 0.58
MEN1 O00255 2/20 0.57
HTT P42858 2/20 0.57
KMT2A Q03164 2/20 0.57
ALDH1A1 P00352 1/20 0.57
MAPT P10636 1/20 0.57
HPGD P15428 1/20 0.57
MAPK1 P28482 1/20 0.57
PDK1 Q15118 2/20 0.55
PDK2 Q15119 2/20 0.55
PDK3 Q15120 2/20 0.55
PDK4 Q16654 2/20 0.55
NAPRT Q6XQN6 1/20 0.54
HSD17B10 Q99714 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14269375 0.87 L3MBTL1 (0.61) EPHX2SMN1; SMN2MEN1HTTKMT2A
SCHEMBL14849461 0.84 PDK1 (0.63) TP53EPHX1TSHREPHX2CDK9
SCHEMBL14362029 0.84 L3MBTL1 (0.56) TP53MEN1HTTKMT2AALDH1A1
SCHEMBL9677254 0.82 PDK1 (0.61) TP53EPHX1TSHREPHX2CDK9
SCHEMBL436619 0.82 PDK1 (0.61) TP53EPHX1TSHREPHX2CDK9
SCHEMBL6789904 0.81 PDK1 (0.60) TP53EPHX1TSHREPHX2CDK9
SCHEMBL14086882 0.80 PDK1 (0.65) TP53EPHX1TSHREPHX2CDK9
SCHEMBL83110 0.79 L3MBTL1 (0.78) TP53EPHX1TSHREPHX2CDK9
SCHEMBL19692687 0.79 TP53 (0.56) TP53EPHX1TSHREPHX2CDK9
SCHEMBL1764510 0.79 MAPT (0.85) TP53EPHX1TSHREPHX2CDK9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7192695-B2 Image forming method using photothermographic material FUJIFILM CORPORATION (JP) 2007-03-20 US disclosed
US-7192695-B2 Image forming method using photothermographic material FUJIFILM CORPORATION (JP) 2007-03-20 US disclosed
US-4546075-A TETRAZOLE, BENZOTHIAZOLE, BENZOXAZOLE, OR BENZIMIDAZOLE COMPOUNDS FUJI PHOTO FILM CO., LTD. (JP) 1985-10-08 US disclosed