SCHEMBL83110

SCHEMBL83110

CC(C)(C)C(=O)Nc1ccccc1

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.78
LMNA P02545 1/20 0.68
PDK1 Q15118 2/20 0.63
PDK2 Q15119 2/20 0.63
PDK3 Q15120 2/20 0.63
PDK4 Q16654 2/20 0.63
NPSR1 Q6W5P4 1/20 0.61
MAPT P10636 4/20 0.60
ALDH1A1 P00352 2/20 0.60
NAPRT Q6XQN6 1/20 0.58
HSD17B10 Q99714 1/20 0.58
HSP90AA1 P07900 1/20 0.56
GPR55 Q9Y2T6 1/20 0.56
CA12 O43570 1/20 0.56
CA1 P00915 1/20 0.56
CA2 P00918 1/20 0.56
CA7 P43166 1/20 0.56
CA9 Q16790 1/20 0.56
CA14 Q9ULX7 1/20 0.56
TP53 P04637 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL384054 0.94 L3MBTL1 (0.69) L3MBTL1LMNAPDK1PDK2PDK3
SCHEMBL28277461 0.92 L3MBTL1 (0.73) L3MBTL1LMNAPDK1PDK2PDK3
SCHEMBL7733701 0.88 L3MBTL1 (1.00) L3MBTL1LMNANPSR1MAPTALDH1A1
SCHEMBL29037529 0.88 L3MBTL1 (0.73) L3MBTL1LMNAPDK1PDK2PDK3
SCHEMBL19501628 0.87 NPSR1 (0.63) L3MBTL1LMNANPSR1MAPTHSD17B10
SCHEMBL14849461 0.86 PDK1 (0.63) L3MBTL1LMNAPDK1PDK2PDK3
SCHEMBL14033573 0.85 LMNA (0.76) L3MBTL1LMNAPDK1PDK2PDK3
SCHEMBL16722802 0.84 NPSR1 (0.76) L3MBTL1LMNANPSR1MAPTALDH1A1
SCHEMBL436619 0.84 PDK1 (0.61) L3MBTL1LMNAPDK1PDK2PDK3
SCHEMBL3129785 0.84 PDK1 (0.67) L3MBTL1LMNAPDK1PDK2PDK3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 493 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119954705-A Indole derivative and preparation method thereof 南阳师范学院 2025-05-09 CN claimed
CN-118063390-A Diamine with naphthyridone structure, thermosetting polyimide resin and preparation method thereof 西北工业大学 2024-05-24 CN claimed
CN-116710516-A Electret meltblown webs with improved filtration performance 博里利斯股份公司 2023-09-05 CN claimed
CN-116178299-A Preparation method of 4H-benzo [ d ] [1,3] oxazin-4-one compound 南京大学 2023-05-30 CN claimed
CN-111187181-B Preparation method of 2- (4-aminophenyl) -2-methylpropanenitrile compound 吉林大学 2023-05-05 CN claimed
CN-111187181-A Preparation method for synthesizing 2- (4-aminophenyl) -2-methylpropanenitrile compound from 2, 2-dimethyl-N-phenyl-propionamide 吉林大学 2020-05-22 CN claimed
WO-2005007094-A2 ASTHMA AND ALLERGIC INFLAMMATION MODULATORS TULARIK INC. (US) 2005-01-27 WO claimed
CN-1342078-A Use of 3-isoxazolidinones and hydroxylamine acids for treatment of infections JOMAA PHARMA GMBH (DE) 2002-03-27 CN claimed
CN-120887811-A Preparation method of N-pivaloyl 2, 4-dichloroaniline 乐平市瑞盛制药有限公司 2025-11-04 CN disclosed
CN-119954705-A Indole derivative and preparation method thereof 南阳师范学院 2025-05-09 CN disclosed
CN-118048636-B Electrocatalytic synthesis method for N-aryl amide 平顶山学院 2024-09-13 CN disclosed
US-12018002-B2 Certain chemical entities, compositions, and methods NEUPHARMA, INC (US) 2024-06-25 US disclosed
CN-118063390-A Diamine with naphthyridone structure, thermosetting polyimide resin and preparation method thereof 西北工业大学 2024-05-24 CN disclosed
CN-118048636-A Electrocatalytic synthesis method for N-aryl amide 平顶山学院 2024-05-17 CN disclosed
US-4731109-A Herbicidal 2-haloacetanilides MONSANTO COMPANY (US) 1988-03-15 US disclosed
EP-0070171-B1 NOVEL PIPERIDINE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME KYOWA HAKKO KOGYO CO., LTD (JP) 1986-10-15 EP disclosed
EP-0070171-A1 Novel piperidine derivatives, processes for preparation thereof and pharmaceutical compositions containing same KYOWA HAKKO KOGYO CO., LTD (JP) 1983-01-19 EP disclosed
US-4328340-A Preparation of 4-amino-6-tert.-butyl-3-alkylthio-1,2,4-triazin-5-(4H)-ones BAYER AKTIENGESELLSCHAFT (DE) 1982-05-04 US disclosed
US-4315094-A Preparation of 4-amino-6-tert.-butyl-3-alkylthio-1,2,4-triazin-5(4H)-one BAYER AKTIENGESELLSCHAFT (DE) 1982-02-09 US disclosed
US-RE30495-E HERBICIDES STAUFFER CHEMICAL COMPANY (US) 1981-01-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12018002-B2 Certain chemical entities, compositions, and methods BRAF, PIK3CA, PLK1 L3MBTL1 3738/4885LMNA 1523/4885PDK1 198/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.