Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBE2M | P61081 | 1/20 | 0.38 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.38 |
| ▸ | CCR5 | P51681 | 9/20 | 0.35 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.32 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.32 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1097420 | 0.94 | UBE2M (0.41) | UBE2MDCUN1D1CCR5P2RY12PDK1 | |
| SCHEMBL1095992 | 0.89 | CASR (0.36) | UBE2MDCUN1D1CCR5P2RY12 | |
| SCHEMBL1095505 | 0.87 | UBE2M (0.38) | UBE2MDCUN1D1P2RY12PDK1PDK2 | |
| SCHEMBL1096420 | 0.85 | CCR5 (0.36) | CCR5ESR1ESR2GPR119 | |
| SCHEMBL1105750 | 0.84 | CCR5 (0.40) | CCR5ESR1ESR2GPR119 | |
| SCHEMBL1095349 | 0.84 | CCR5 (0.35) | UBE2MDCUN1D1CCR5ESR1ESR2 | |
| SCHEMBL1096776 | 0.82 | CCR5 (0.39) | CCR5ESR1ESR2GPR119 | |
| SCHEMBL1095287 | 0.82 | ESR1 (0.37) | UBE2MDCUN1D1CCR5ESR1ESR2 | |
| SCHEMBL1096874 | 0.82 | CCR5 (0.40) | CCR5 | |
| SCHEMBL1096075 | 0.81 | CASR (0.34) | UBE2MDCUN1D1P2RY12GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8153658-B2 | Piperidine derivative or salt thereof | ASTELLAS PHARMA, INC. (JP) | 2012-04-10 | — | — | US | disclosed |
| US-20100029687-A1 | PIPERIDINE DERIVATIVE OR SALT THEREOF | ASTELLAS PHARMA INC. (JP) | 2010-02-04 | — | — | US | disclosed |
| EP-2085383-A1 | PIPERIDINE DERIVATIVES OR SALTS THEREOF | Astellas Pharma Inc. (JP) | 2009-08-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029687-A1 | PIPERIDINE DERIVATIVE OR SALT THEREOF | CASR, CYP2R1, HCAR1 | UBE2M 4660/4885DCUN1D1 2737/4885CCR5 542/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.