Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.58 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.58 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.58 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.54 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10981330 | 0.99 | CACNA2D1 (0.56) | CACNA2D1CACNA1BCACNB1CACNA1CNPSR1 | |
| SCHEMBL10981812 | 0.84 | MEN1 (0.59) | NPSR1MEN1KMT2AATMALDH1A1 | |
| SCHEMBL1691475 | 0.81 | SLC6A9 (0.74) | CACNA2D1CACNA1BCACNB1CACNA1CNPSR1 | |
| SCHEMBL5027817 | 0.80 | CACNA2D1 (0.63) | CACNA2D1CACNA1BCACNB1CACNA1CNPSR1 | |
| SCHEMBL7266659 | 0.79 | ALDH1A1 (0.57) | CACNA2D1CACNA1BCACNB1CACNA1CKDM4E | |
| SCHEMBL8196250 | 0.78 | OPRM1 (0.62) | CACNA2D1CACNA1BCACNB1CACNA1CNPSR1 | |
| SCHEMBL10930361 | 0.78 | CACNA2D1 (0.65) | CACNA2D1CACNA1BCACNB1CACNA1CNPSR1 | |
| SCHEMBL17549667 | 0.77 | SLC6A4 (0.67) | KMT2AATMSLC6A4SLC6A3ALDH1A1 | |
| Belarizine SCHEMBL2108057 | 0.77 | ATM (0.73) | NPSR1KDM4EMEN1KMT2AATM | |
| SCHEMBL4875267 | 0.77 | ALDH1A1 (0.79) | KDM4EMEN1KMT2ASLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4528194-A | 2-(4-Diphenylmethylpiperazinyl)-1-phenyl alkanol or their salts, a process for their production and a cerebral circulation-improving drug | NIPPON CHEMIPHAR CO., LTD. (JP) | 1985-07-09 | — | — | US | disclosed |