Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | GRM5 | P41594 | 1/20 | 0.57 |
| ▸ | GFER | P55789 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.52 |
| ▸ | ME2 | P23368 | 1/20 | 0.52 |
| ▸ | ME1 | P48163 | 1/20 | 0.52 |
| ▸ | ME3 | Q16798 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11120650 | 0.89 | GFER (0.57) | MAPTALDH1A1GRM5GFERATM | |
| Hydrochloric Acid SCHEMBL10979991 | 0.88 | GFER (0.56) | MAPTALDH1A1GRM5GFERATM | |
| SCHEMBL4375739 | 0.77 | MAPT (0.64) | MAPTALDH1A1GFERATMPOLB | |
| SCHEMBL6706289 | 0.76 | ME2 (0.82) | MAPTALDH1A1GRM5GFERATM | |
| SCHEMBL19442006 | 0.74 | ALDH1A1 (0.69) | MAPTALDH1A1GRM5L3MBTL1ME2 | |
| SCHEMBL6283959 | 0.74 | GRM5 (0.67) | MAPTALDH1A1GRM5L3MBTL1ME2 | |
| SCHEMBL1902638 | 0.73 | GRM5 (1.00) | MAPTALDH1A1GRM5ME2ME1 | |
| SCHEMBL11980694 | 0.73 | ALDH1A1 (0.67) | MAPTALDH1A1GRM5L3MBTL1HSD17B10 | |
| SCHEMBL14438077 | 0.73 | MAPT (0.74) | MAPTALDH1A1POLBMEN1KMT2A | |
| SCHEMBL27876284 | 0.72 | ALDH1A1 (1.00) | MAPTALDH1A1GRM5L3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0077720-B1 | BIPHENYL ALKYL CARBOXYLATED DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINES | PIERRE FABRE S.A. (FR) | 1984-07-25 | — | — | EP | claimed |
| US-4510142-A | ANTIINFLAMMATORY OR ANALGESIC AGNET | PIERRE FABRE S.A. (FR) | 1985-04-09 | — | — | US | disclosed |