Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | GRM5 | P41594 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10979991 | 0.99 | GFER (0.56) | GFERATMALDH1A1MAPTGRM5 | |
| SCHEMBL10983798 | 0.89 | MAPT (0.57) | GFERATMALDH1A1MAPTGRM5 | |
| SCHEMBL10980222 | 0.82 | ALDH1A1 (0.50) | ALDH1A1MAPTGRM5L3MBTL1LMNA | |
| SCHEMBL11839428 | 0.73 | MAPT (0.49) | ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL6706289 | 0.71 | ME2 (0.82) | GFERATMALDH1A1MAPTGRM5 | |
| SCHEMBL19068065 | 0.70 | CYP4F2 (0.54) | ALDH1A1 | |
| SCHEMBL4211652 | 0.70 | GAA (0.63) | GFERALDH1A1LMNA | |
| SCHEMBL19442006 | 0.69 | ALDH1A1 (0.69) | ALDH1A1MAPTGRM5L3MBTL1LMNA | |
| Bifeprofen SCHEMBL2109705 | 0.69 | L3MBTL1 (0.44) | ATMALDH1A1L3MBTL1POLB | |
| SCHEMBL6283959 | 0.69 | GRM5 (0.67) | ALDH1A1MAPTGRM5L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0077720-B1 | BIPHENYL ALKYL CARBOXYLATED DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINES | PIERRE FABRE S.A. (FR) | 1984-07-25 | — | — | EP | claimed |