Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 1.00 |
| ▸ | HTT | P42858 | 1/20 | 0.72 |
| ▸ | GRM5 | P41594 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | CASP3 | P42574 | 1/20 | 0.54 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.54 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27876376 | 0.84 | HTT (0.80) | ALDH1A1HTTPKMLMNAUSP2 | |
| SCHEMBL28038078 | 0.83 | HTT (0.97) | ALDH1A1HTTPKMLMNANPC1 | |
| SCHEMBL19442006 | 0.81 | ALDH1A1 (0.69) | ALDH1A1GRM5HSD17B10LMNAMAPK1 | |
| SCHEMBL11980694 | 0.81 | ALDH1A1 (0.67) | ALDH1A1GRM5HSD17B10MAPK1MAPT | |
| SCHEMBL24711247 | 0.78 | ALDH1A1 (0.77) | ALDH1A1HTTHSD17B10LMNAUSP2 | |
| SCHEMBL27859664 | 0.77 | HTT (0.71) | ALDH1A1HTTPKMLMNAPOLB | |
| Hydrochloric Acid SCHEMBL11395487 | 0.77 | HRH3 (0.65) | ALDH1A1PKMLMNA | |
| SCHEMBL1902638 | 0.76 | GRM5 (1.00) | ALDH1A1GRM5LMNAMAPTNPC1 | |
| SCHEMBL9125887 | 0.74 | GRM5 (0.72) | ALDH1A1HTTGRM5HSD17B10LMNA | |
| SCHEMBL6283959 | 0.74 | GRM5 (0.67) | ALDH1A1HTTGRM5HSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102482249-A | TOFA analogs for treating skin disorders or conditions | VALOCOR THERAPEUTICS INC | 2012-05-30 | — | — | CN | claimed |
| CN-102482249-A | TOFA analogs for treating skin disorders or conditions | VALOCOR THERAPEUTICS INC | 2012-05-30 | — | — | CN | disclosed |