Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 7/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 6/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10988930 | 0.84 | GRM2 (0.47) | NR1H2NR1H3GRM2 | |
| Flurochloridone SCHEMBL9668444 | 0.81 | DRD2 (0.43) | ALDH1A1LMNAMAPTGRM2SMN1; SMN2 | |
| Flurochloridone SCHEMBL29471429 | 0.81 | DRD2 (0.43) | ALDH1A1LMNAMAPTGRM2SMN1; SMN2 | |
| Flurochloridone SCHEMBL8539437 | 0.81 | DRD2 (0.43) | ALDH1A1LMNAMAPTGRM2SMN1; SMN2 | |
| Flurochloridone SCHEMBL54056 | 0.81 | DRD2 (0.43) | ALDH1A1LMNAMAPTGRM2SMN1; SMN2 | |
| Flurochloridone SCHEMBL10985578 | 0.81 | DRD2 (0.43) | ALDH1A1LMNAMAPTGRM2SMN1; SMN2 | |
| Flurochloridone SCHEMBL9668435 | 0.81 | DRD2 (0.43) | ALDH1A1LMNAMAPTGRM2SMN1; SMN2 | |
| SCHEMBL10986130 | 0.79 | FADS1 (0.44) | ALDH1A1LMNAMAPTGRM2 | |
| SCHEMBL10967769 | 0.79 | ALDH1A1 (0.47) | ALDH1A1GRM2ALOX15TSHR | |
| SCHEMBL10971914 | 0.78 | TRPA1 (0.35) | ALDH1A1ALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4505737-A | HALOGENATED PHENYLPYRROLIDONE AND HALOALKYLPHOSPHONIC ACID | STAUFFER CHEMICAL COMPANY (US) | 1985-03-19 | — | — | US | disclosed |
| US-4428767-A | A PYRROLIDONE AND A CYCLOHEXENEDIONE | STAUFFER CHEMICAL COMPANY (US) | 1984-01-31 | — | — | US | disclosed |
| US-4416684-A | PYRROLIDONE AND M-UREIDOPHENYL CARBAMATE | STAUFFER CHEMICAL COMPANY (US) | 1983-11-22 | — | — | US | disclosed |
| US-4317673-A | MIXTURE OF /-TRIFLUOROPHENYL; 3-CHLORO, 4-CHLOROMETHYL-2-PYRROLIDONE AND AN N-P-CHLOROPHENOXYPHENYL-N*,N*-DIALKYL UREA | STAUFFER CHEMICAL COMPANY (US) | 1982-03-02 | — | — | US | disclosed |
| EP-0015453-B1 | SYNERGISTIC HERBICIDAL COMPOSITIONS AND METHOD FOR CONTROLLING UNDESIRABLE VEGETATION | STAUFFER CHEMICAL COMPANY (US) | 1981-11-04 | — | — | EP | disclosed |
| US-4263038-A | 3-AMINO-TRIAZOLE AND A PYRROLIDONE | STAUFFER CHEMICAL COMPANY (US) | 1981-04-21 | — | — | US | disclosed |
| EP-0015453-A2 | Synergistic herbicidal compositions and method for controlling undesirable vegetation | STAUFFER CHEMICAL COMPANY (US) | 1980-09-17 | — | — | EP | disclosed |
| US-4210589-A | CYCLIZATION | STAUFFER CHEMICAL COMPANY (US) | 1980-07-01 | — | — | US | disclosed |
| US-4110105-A | Aromatic N-substituted halo-substituted-2-pyrrolidinones and their utility as herbicides | STAUFFER CHEMICAL COMPANY (US) | 1978-08-29 | — | — | US | disclosed |