Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8886689 | 0.95 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL5709356 | 0.87 | — | — | |
| SCHEMBL14224731 | 0.79 | SLC6A2 (0.48) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL27680712 | 0.78 | TRPM5 (0.43) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8887381 | 0.76 | — | — | |
| SCHEMBL8886391 | 0.76 | SLC10A2 (0.41) | — | |
| SCHEMBL8887743 | 0.74 | CHRNB2 (0.43) | — | |
| SCHEMBL8887938 | 0.73 | TRPM5 (0.44) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL10977771 | 0.71 | — | — | |
| Alcohol SCHEMBL8887876 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0035363-B1 | INDANE DERIVATIVES, METHODS OF THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | KEFALAS A/S (DK) | 1985-05-02 | — | — | EP | disclosed |
| US-4443448-A | ANALGESICS, ANTIDEPRESSANTS, NEUROLEPTICS | KEFALAS A/S (DK) | 1984-04-17 | — | — | US | disclosed |
| EP-0035363-A1 | Indane derivatives, methods of their preparation and compositions containing them | KEFALAS A/S (DK) | 1981-09-09 | — | — | EP | disclosed |