Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.47 |
| ▸ | TRPM5 | Q9NZQ8 | 2/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8886689 | 0.83 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8885782 | 0.79 | DRD2 (0.46) | TRPM5CYP19A1HTR2AHTR2CHTR2B | |
| SCHEMBL28040971 | 0.79 | SIGMAR1 (0.48) | SIGMAR1HTR2AHTR2CHTR2BHRH3 | |
| SCHEMBL5709410 | 0.79 | SIGMAR1 (0.48) | SIGMAR1HTR2AHTR2CHTR2BHRH3 | |
| SCHEMBL13051102 | 0.79 | SIGMAR1 (0.48) | SIGMAR1HTR2AHTR2CHTR2BHRH3 | |
| SCHEMBL13906155 | 0.79 | SIGMAR1 (0.48) | SIGMAR1HTR2AHTR2CHTR2BHRH3 | |
| SCHEMBL10985667 | 0.79 | SLC6A2 (0.49) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8887938 | 0.77 | TRPM5 (0.44) | SLC6A2SLC6A4SLC6A3TRPM5 | |
| SCHEMBL12200284 | 0.76 | ALDH1A1 (0.45) | SLC6A2SLC6A4SLC6A3ALDH1A1ALDH2 | |
| SCHEMBL6149416 | 0.76 | ALDH1A1 (0.45) | SLC6A2SLC6A4SLC6A3ALDH1A1ALDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7358399-B2 | Process for the preparation of N,N-diisopropyl-3-(2-hydroxy-5-methylphenyl)-3-phenyl-propaneamine | CHEMI SPA (IT) | 2008-04-15 | — | — | US | disclosed |