Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10985667 | 0.95 | SLC6A2 (0.49) | SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL14224731 | 0.83 | SLC6A2 (0.48) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5709356 | 0.81 | — | — | |
| SCHEMBL8887381 | 0.81 | — | — | |
| SCHEMBL8886391 | 0.80 | SLC10A2 (0.41) | — | |
| SCHEMBL8887743 | 0.78 | CHRNB2 (0.43) | — | |
| SCHEMBL8887938 | 0.77 | TRPM5 (0.44) | SLC6A2SLC6A4SLC6A3 | |
| Alcohol SCHEMBL8887876 | 0.73 | — | — | |
| SCHEMBL8887868 | 0.73 | — | — | |
| SCHEMBL27680712 | 0.73 | TRPM5 (0.43) | SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5643784-A | TREATMENT OF ANXIETY, DEPRESSION, SLEEPING DISORDERS, SCHIZOPHRENIA AND MIGRAINE | H, LUNDBECK A/S (DK) | 1997-07-01 | — | — | US | disclosed |
| EP-0560868-B1 | INDAN DERIVATIVES | LUNDBECK & CO AS H (DK) | 1995-04-19 | — | — | EP | disclosed |
| EP-0560868-A1 | INDAN DERIVATIVES. | LUNDBECK & CO AS H (DK) | 1993-09-22 | — | — | EP | disclosed |
| WO-1992010192-A1 | INDAN DERIVATIVES | H. LUNDBECK A/S (DK) | 1992-06-25 | — | — | WO | disclosed |