Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | RHEB | Q15382 | 1/20 | 0.37 |
| ▸ | FBP1 | P09467 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | PNMT | P11086 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30753726 | 0.84 | LMNA (0.45) | LMNATSHRRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL1705482 | 0.80 | RAB9A (0.46) | LMNATSHRRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL11028082 | 0.80 | PNMT (0.44) | LMNATSHRRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL29707978 | 0.80 | RAB9A (0.42) | LMNATSHRRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL27942919 | 0.80 | RAB9A (0.46) | LMNATSHRRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL3790646 | 0.80 | RAB9A (0.42) | LMNATSHRRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL10937002 | 0.80 | RAB9A (0.42) | LMNATSHRRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL5576227 | 0.77 | CYP1A2 (0.50) | LMNATSHRRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL28101080 | 0.77 | POLB (0.61) | LMNARAB9ANPC1SMN1; SMN2POLB | |
| SCHEMBL10144132 | 0.77 | PTGS2 (0.47) | LMNATSHRRAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110713448-B | Preparation method of carbon dioxide-participated dithioacetal | 清华大学 | 2020-08-18 | — | — | CN | disclosed |
| CN-110713448-A | Preparation method of carbon dioxide-participated dithioacetal | 清华大学 | 2020-01-21 | — | — | CN | disclosed |
| US-4496720-A | REACTING SILATED THIO WITH ORGANIC HALIDE, SULATE OR SULFONATE IN PRESENCE OF HEXAMETHYLPHOSPHORIC TRIAMIDE | GIST-BROCADES N.V. (NL) | 1985-01-29 | — | — | US | disclosed |