Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 4/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10977643 | 0.88 | NPC1 (0.38) | — | |
| SCHEMBL10984689 | 0.88 | MAPK14 (0.39) | BRD4MAPK14 | |
| SCHEMBL10989413 | 0.87 | BRD4 (0.42) | BRD4HTR2AHTR2CPTGDR2BTK | |
| SCHEMBL11053638 | 0.86 | GAA (0.43) | — | |
| SCHEMBL11088526 | 0.85 | BRD4 (0.47) | BRD4HTR2AHTR2CPTGDR2BTK | |
| SCHEMBL10986271 | 0.85 | ALDH1A1 (0.45) | — | |
| SCHEMBL11080541 | 0.83 | BRD4 (0.42) | BRD4HTR2AHTR2CPTGDR2BTK | |
| SCHEMBL10982627 | 0.82 | BRD4 (0.43) | BRD4HTR2AHTR2CPTGDR2BTK | |
| SCHEMBL10986261 | 0.77 | — | — | |
| SCHEMBL11205806 | 0.77 | PTGDR2 (0.46) | BRD4PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499279-A | ANTIDIABETIC AND HYPOGLYCEMIC AGENTS | SANDOZ, INC. (US) | 1985-02-12 | — | — | US | disclosed |
| US-4419353-A | ANTIDIABETIC AGENTS | SANDOZ, INC. (US) | 1983-12-06 | — | — | US | disclosed |
| US-4397850-A | HYPOGLYCEMIC, ANTIDIABETIC | SANDOZ, INC. (US) | 1983-08-09 | — | — | US | disclosed |
| US-4336379-A | ANTIDIABETIC AGENTS | SANDOZ, INC. (US) | 1982-06-22 | — | — | US | disclosed |