Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSV | O60911 | 1/20 | 0.54 |
| ▸ | CTSL | P07711 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | TSHR | P16473 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | GHSR | Q92847 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10984770 | 0.92 | ALDH1A1 (0.57) | CTSVCTSLKDM4ETSHRALDH1A1 | |
| SCHEMBL10983500 | 0.85 | CTSV (0.59) | CTSVCTSLKDM4EALDH1A1GHSR | |
| SCHEMBL10978475 | 0.85 | CTSV (0.59) | CTSVCTSLKDM4EALDH1A1GHSR | |
| SCHEMBL10978966 | 0.85 | CTSV (0.59) | CTSVCTSLKDM4EALDH1A1GHSR | |
| SCHEMBL9132050 | 0.79 | KDM4E (0.59) | KDM4ETSHRALDH1A1LMNAMAPK1 | |
| SCHEMBL7418911 | 0.78 | MTNR1A (0.51) | CTSVCTSLKDM4EALDH1A1LMNA | |
| SCHEMBL19739582 | 0.77 | TSHR (0.59) | KDM4ETSHRALDH1A1LMNAMAPK1 | |
| SCHEMBL6990848 | 0.76 | ALOX5 (0.53) | KDM4EALDH1A1LMNAHSD17B10MAPT | |
| SCHEMBL9052001 | 0.75 | MTNR1A (0.48) | KDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL10981279 | 0.74 | HRH3 (0.53) | CTSVCTSLKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4493843-A | Indole and indoline carboxylic acid compounds and method of use | MAY & BAKER LIMITED (GB) | 1985-01-15 | — | — | US | disclosed |
| EP-0042298-B1 | INDOLE AND INDOLINE DERIVATIVES | MAY & BAKER LIMITED (GB) | 1984-09-12 | — | — | EP | disclosed |
| EP-0042298-A1 | Indole and indoline derivatives | MAY & BAKER LIMITED (GB) | 1981-12-23 | — | — | EP | disclosed |