Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.48 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MPL | P40238 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7418911 | 0.88 | MTNR1A (0.51) | MTNR1AMTNR1BCDK5CDK5R1KDM4E | |
| SCHEMBL16686988 | 0.85 | MTNR1A (0.49) | MTNR1AMTNR1BCDK5CDK5R1KDM4E | |
| SCHEMBL7427823 | 0.82 | MTNR1A (0.48) | MTNR1AMTNR1BCDK5CDK5R1RIPK1 | |
| SCHEMBL7422802 | 0.78 | ALOX5 (0.44) | MTNR1AMTNR1BCDK5CDK5R1KDM4E | |
| SCHEMBL10991306 | 0.75 | CTSV (0.54) | KDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL6993928 | 0.75 | NR4A2 (0.46) | MTNR1AMTNR1BCDK5CDK5R1NR4A2 | |
| SCHEMBL5851103 | 0.75 | KDM4E (0.52) | CDK5CDK5R1KDM4EKIF11PIM1 | |
| SCHEMBL28872605 | 0.74 | CDK4 (0.42) | MTNR1AMTNR1BCDK5CDK5R1KDM4E | |
| SCHEMBL10984770 | 0.74 | ALDH1A1 (0.57) | KDM4EHSD17B10MEN1KMT2AL3MBTL1 | |
| SCHEMBL19644057 | 0.74 | NR4A2 (0.51) | CDK5CDK5R1KIF11PIM1PIM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0734386-A1 | PLATELET ACTIVATING FACTOR ANTAGONISTS: IMIDAZOPYRIDINE INDOLES | Abbott Laboratories (US) | 1996-10-02 | — | — | EP | disclosed |
| WO-1995016687-A1 | PLATELET ACTIVATING FACTOR ANTAGONISTS: IMIDAZOPYRIDINE INDOLES | ABBOTT LABORATORIES (US) | 1995-06-22 | — | — | WO | disclosed |