Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 4/20 | 0.61 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.46 |
| ▸ | PTGES | O14684 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10994648 | 0.86 | MAPT (0.48) | PIN1HPGDMAPTLMNAKMT2A | |
| SCHEMBL10994011 | 0.86 | PIN1 (0.56) | PIN1HPGDMAPTLMNAHTT | |
| SCHEMBL10992514 | 0.86 | MAPT (0.51) | PIN1HPGDMAPTLMNAHTT | |
| SCHEMBL11026917 | 0.80 | ALOX5 (0.54) | PIN1HPGDMAPTLMNAHTT | |
| SCHEMBL6237528 | 0.79 | KMT2A (0.65) | PIN1HPGDMAPTLMNAHTT | |
| SCHEMBL28475326 | 0.79 | PIN1 (0.55) | PIN1MAPTLMNAHTTRECQL | |
| SCHEMBL10675736 | 0.79 | LMNA (0.42) | PIN1HPGDMAPTLMNAHTT | |
| SCHEMBL3799780 | 0.79 | ALDH1A1 (0.47) | PIN1HPGDMAPTLMNAHTT | |
| SCHEMBL10988253 | 0.78 | HPGD (0.66) | PIN1HPGDMAPTLMNAHTT | |
| SCHEMBL10990381 | 0.77 | LMNA (0.46) | PIN1HPGDMAPTLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4521426-A | Pesticidal bicyclooxyheterocyclyl aroyl ureas | UNION CARBIDE CORPORATION (US) | 1985-06-04 | — | — | US | disclosed |