Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | ICMT | O60725 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26416944 | 0.80 | CA12 (0.57) | L3MBTL1NPC1RAB9ASMN1; SMN2PSIP1 | |
| SCHEMBL4163019 | 0.78 | RAB9A (0.47) | L3MBTL1NPC1RAB9ASMN1; SMN2PSIP1 | |
| SCHEMBL5546737 | 0.78 | L3MBTL1 (0.43) | L3MBTL1NPC1RAB9ASMN1; SMN2PSIP1 | |
| SCHEMBL6233644 | 0.78 | PSIP1 (0.50) | L3MBTL1NPC1RAB9ASMN1; SMN2PSIP1 | |
| SCHEMBL4629056 | 0.78 | RAB9A (0.51) | L3MBTL1NPC1RAB9ASMN1; SMN2PSIP1 | |
| SCHEMBL11505439 | 0.76 | MAPT (0.47) | SMN1; SMN2MAPTHTTALDH1A1CYP1A2 | |
| SCHEMBL3910980 | 0.75 | L3MBTL1 (0.59) | L3MBTL1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL4158643 | 0.75 | SMN1; SMN2 (0.44) | L3MBTL1NPC1RAB9ASMN1; SMN2PSIP1 | |
| SCHEMBL27489390 | 0.75 | SMN1; SMN2 (0.58) | L3MBTL1SMN1; SMN2PSIP1MAPTHTT | |
| SCHEMBL8751587 | 0.74 | MAPT (0.50) | L3MBTL1NPC1RAB9ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4500715-A | CHEMICAL INTERMEDIATES FOR PLANT SAFENING AGENTS AND DYES | BAYER AKTIENGESELLSCHAFT (DE) | 1985-02-19 | — | — | US | disclosed |
| US-4268438-A | Cationic 1,3,4-thiadiazole dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1981-05-19 | — | — | US | disclosed |