Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.43 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4163019 | 0.88 | RAB9A (0.47) | SMN1; SMN2RAB9ANPC1PSIP1L3MBTL1 | |
| SCHEMBL6232014 | 0.78 | SMN1; SMN2 (0.53) | SMN1; SMN2PSIP1L3MBTL1MAPTGAA | |
| SCHEMBL29563275 | 0.78 | SMN1; SMN2 (0.53) | SMN1; SMN2PSIP1L3MBTL1MAPTGAA | |
| SCHEMBL4165647 | 0.76 | MEN1 (0.46) | SMN1; SMN2RAB9ANPC1KAT2BMAPT | |
| SCHEMBL6974913 | 0.76 | L3MBTL1 (0.38) | SMN1; SMN2RAB9ANPC1PSIP1KAT2B | |
| SCHEMBL6233644 | 0.75 | PSIP1 (0.50) | SMN1; SMN2RAB9ANPC1PSIP1L3MBTL1 | |
| SCHEMBL5546737 | 0.75 | L3MBTL1 (0.43) | SMN1; SMN2RAB9ANPC1PSIP1L3MBTL1 | |
| SCHEMBL4629056 | 0.75 | RAB9A (0.51) | SMN1; SMN2RAB9ANPC1PSIP1L3MBTL1 | |
| SCHEMBL10994002 | 0.75 | L3MBTL1 (0.43) | SMN1; SMN2RAB9ANPC1PSIP1L3MBTL1 | |
| SCHEMBL6971190 | 0.74 | ALDH1A1 (0.46) | SMN1; SMN2RAB9ANPC1L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090088438-A1 | NEW TYROSINE DERIVATIVES AS PPARy MODULATORS | LABORATORIOS SALVAT, S.A. (ES) | 2009-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090088438-A1 | NEW TYROSINE DERIVATIVES AS PPARy MODULATORS | PPARG, PPARD, TYRO3 | SMN1; SMN2 4621/4885RAB9A 2235/4885NPC1 3120/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.