Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.57 |
| ▸ | DRD2 | P14416 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10984567 | 0.86 | HTR1A (0.50) | HTR1ADRD2MEN1KMT2ADRD4 | |
| SCHEMBL10987790 | 0.76 | GAA (0.54) | HTR1ADRD2MEN1KMT2ACYP1A2 | |
| SCHEMBL10990977 | 0.76 | LMNA (0.54) | KMT2ACYP1A2CYP2C19MAPT | |
| Mezilamine SCHEMBL2109086 | 0.75 | HTR1A (1.00) | HTR1ADRD2DRD4 | |
| SCHEMBL979110 | 0.74 | PDE4A (0.43) | HTR1ADRD2CYP1A2PDE4ACYP2C19 | |
| SCHEMBL1397057 | 0.74 | ALDH1A1 (0.39) | HTR1ADRD2CYP1A2 | |
| Hydrochloric Acid SCHEMBL11565715 | 0.73 | HTR1A (0.71) | HTR1ADRD2DRD4 | |
| SCHEMBL28960187 | 0.72 | KMT2A (0.37) | HTR1ADRD2MEN1KMT2ACYP1A2 | |
| SCHEMBL10958985 | 0.72 | HSP90AB1 (0.36) | HTR1ADRD2DRD4 | |
| SCHEMBL10990838 | 0.71 | XDH (0.41) | HTR1ADRD2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4528026-A | 2-(Or4-)amino-5-alkylthio-pyrimidine herbicides | PRODUITS CHIMIQUES UGINE KUHLMANN (FR) | 1985-07-09 | — | — | US | disclosed |
| US-4166852-A | ANALGESICS, ANTISEROTONINE AGENTS, PSYCHOTROPES | PRODUITS CHIMIQUES UGINE KUHLMANN (FR) | 1979-09-04 | — | — | US | disclosed |