SCHEMBL10994136

SCHEMBL10994136

Cc1cc2ccccc2c(CS(=O)(=O)O)c1C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.38
CYP2A6 P11509 3/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
HTR2A P28223 1/20 0.38
ALDH1A1 P00352 3/20 0.38
HPGD P15428 1/20 0.38
HSD17B10 Q99714 1/20 0.38
GPR35 Q9HC97 2/20 0.36
POLB P06746 1/20 0.36
ACP1 P24666 1/20 0.36
SLC2A1 P11166 2/20 0.35
TSHR P16473 1/20 0.35
CYP2D6 P10635 1/20 0.35
PTGS1 P23219 1/20 0.35
PTGS2 P35354 1/20 0.35
KDM4E B2RXH2 2/20 0.34
GAA P10253 1/20 0.34
SUMO2 P61956 1/20 0.34
SUMO1 P63165 1/20 0.34
SENP7 Q9BQF6 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10423975 0.80 TSHR (0.46) CYP1A2CYP2A6ALDH1A1HPGDHSD17B10
SCHEMBL7915027 0.79 CYP1A2 (0.45) CYP1A2CYP2A6L3MBTL1HTR2AALDH1A1
SCHEMBL8042385 0.75 CYP1A2 (0.45) CYP1A2CYP2A6L3MBTL1HTR2AALDH1A1
Hydrochloric Acid SCHEMBL28315407 0.75 FABP4 (0.37) ALDH1A1ACP1KDM4EGAAMAPK1
SCHEMBL437289 0.75 CYP2D6 (0.51) CYP1A2CYP2A6ALDH1A1HPGDHSD17B10
SCHEMBL814436 0.74 CYP1A2 (0.44) CYP1A2CYP2A6L3MBTL1HTR2AALDH1A1
SCHEMBL28428509 0.74 L3MBTL1 (0.64) CYP1A2CYP2A6L3MBTL1HTR2AALDH1A1
SCHEMBL11273396 0.73 CYP1A2 (0.40) CYP1A2CYP2A6L3MBTL1HTR2AALDH1A1
SCHEMBL1702486 0.73 CTRB1 (0.47) CYP1A2ALDH1A1HPGDHSD17B10SLC2A1
Ammonia Solution, Strong SCHEMBL11422698 0.73 CYP2D6 (0.50) CYP1A2CYP2A6ALDH1A1HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0066278-B1 TRANSFER PRINTING SHEET, PROCESS FOR ITS MANUFACTURE AND ITS USE HOECHST AKTIENGESELLSCHAFT (DE) 1985-10-30 EP disclosed
US-4422854-A Transfer printing support, process for the manufacture thereof, with blue azo dye:di-cyano-nitro-phenyl-azo aniline HOECHST AKTIENGESELLSCHAFT (DE) 1983-12-27 US disclosed
EP-0066278-A1 Transfer printing sheet, process for its manufacture and its use HOECHST AKTIENGESELLSCHAFT (DE) 1982-12-08 EP disclosed