Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10986888 | 0.88 | POLB (0.55) | ALDH1A1MAPTPOLBKMT2AKDM4E | |
| SCHEMBL7444058 | 0.87 | ALDH1A1 (0.44) | REV1ALDH1A1MAPTPOLBDRD2 | |
| SCHEMBL10995044 | 0.85 | ALDH1A1 (0.48) | ALDH1A1POLBDRD2DRD4DRD3 | |
| SCHEMBL10992553 | 0.83 | ALDH1A1 (0.54) | ALDH1A1MAPTKMT2AKDM4ETDP1 | |
| SCHEMBL10997102 | 0.83 | MEN1 (0.52) | REV1ALDH1A1MAPTPOLBCA1 | |
| SCHEMBL10991908 | 0.83 | RAB9A (0.56) | ALDH1A1MAPTPOLBCA1CA2 | |
| SCHEMBL10996385 | 0.83 | POLB (0.51) | REV1ALDH1A1MAPTPOLBCA1 | |
| SCHEMBL10993177 | 0.82 | POLB (0.42) | ALDH1A1MAPTPOLBCA1CA2 | |
| SCHEMBL10994397 | 0.81 | ALDH1A1 (0.58) | ALDH1A1MAPTPOLBKMT2ATDP1 | |
| SCHEMBL10994263 | 0.81 | ALDH1A1 (0.41) | REV1ALDH1A1MAPTPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4558129-A | Benzodioxanyl-hydroxyethylene-piperazinyl acetanilides which effect calcium entry and β-blockade | SYNTEX (U.S.A.) INC. (US) | 1985-12-10 | — | — | US | disclosed |