Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7443888 | 0.89 | POLB (0.48) | ALDH1A1HTTRECQLNPSR1SMN1; SMN2 | |
| SCHEMBL10994604 | 0.87 | REV1 (0.48) | ALDH1A1DRD4DRD2DRD3REV1 | |
| SCHEMBL7436573 | 0.87 | HTT (0.47) | ALDH1A1DRD4DRD2DRD3HTT | |
| SCHEMBL7447128 | 0.85 | RAB9A (0.52) | ALDH1A1HTTNPSR1SMN1; SMN2POLB | |
| SCHEMBL7440389 | 0.85 | MEN1 (0.47) | ALDH1A1REV1SMN1; SMN2POLBCYP3A4 | |
| SCHEMBL7428126 | 0.85 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2POLBLMNA | |
| SCHEMBL7439756 | 0.84 | POLB (0.45) | ALDH1A1NPSR1SMN1; SMN2POLBCYP3A4 | |
| SCHEMBL7433767 | 0.83 | DRD4 (0.53) | ALDH1A1DRD4DRD2DRD3 | |
| SCHEMBL7439415 | 0.83 | POLB (0.49) | ALDH1A1HTTRECQLNPSR1SMN1; SMN2 | |
| SCHEMBL7441217 | 0.82 | ALDH1A1 (0.56) | ALDH1A1HTTSMN1; SMN2POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |