Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | AIMP2 | Q13155 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10997582 | 0.91 | LMNA (0.36) | ALDH1A1POLBSMN1; SMN2MAPTLMNA | |
| SCHEMBL11000014 | 0.90 | POLB (0.42) | ALDH1A1AIMP2POLBSMN1; SMN2MAPT | |
| SCHEMBL7440732 | 0.88 | MAPT (0.38) | ALDH1A1AIMP2POLBSMN1; SMN2MAPT | |
| SCHEMBL7445153 | 0.81 | MAPT (0.36) | ALDH1A1AIMP2POLBSMN1; SMN2MAPT | |
| SCHEMBL10994604 | 0.81 | REV1 (0.48) | ALDH1A1POLBSMN1; SMN2MAPTLMNA | |
| SCHEMBL10986888 | 0.80 | POLB (0.55) | ALDH1A1AIMP2POLBSMN1; SMN2MAPT | |
| SCHEMBL10991908 | 0.80 | RAB9A (0.56) | ALDH1A1AIMP2POLBSMN1; SMN2MAPT | |
| SCHEMBL10994845 | 0.80 | CCR2 (0.38) | ALDH1A1AIMP2POLBLMNANPSR1 | |
| SCHEMBL10991013 | 0.79 | ALOX15 (0.51) | ALDH1A1AIMP2POLBSMN1; SMN2MAPT | |
| SCHEMBL10991994 | 0.79 | POLB (0.47) | ALDH1A1POLBSMN1; SMN2MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4558129-A | Benzodioxanyl-hydroxyethylene-piperazinyl acetanilides which effect calcium entry and β-blockade | SYNTEX (U.S.A.) INC. (US) | 1985-12-10 | — | — | US | disclosed |